Abnova Corporation

mRNA Cap 2'-O-Methyltransferase

Product Code:
DM0018
Regulatory Status:
GMP grade
Application:
In vitro transcription (IVT)
Storage:
Store at -20C.Aliquot to avoid repeated freezing and thawing.
 

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This product comes from: Taiwan.
Typical lead time: 14-21 working days.
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Further Information

Description:
mRNA Cap 2'-O-Methyltransferase can add a methyl group to the 2'-O of the first nucleotide of the Cap0 structure, [m7GpppN1(pN)x-OH(3')], next to the RNA 5' end. Methylation of capped mRNA from Cap 0 to Cap1 naturally exists in eukaryocyte, where the Cap1 structure shows an important effect for translation, thus for expression as well. This product doesn?t show a reactivity to RNA substrate other than RNA with Cap0 structure.
Form:
Liquid
Purity:
95% ≤
Recommended Dilutions:
Methylate the 2'-O of the first nucleotide of the Cap0 structure, to realize mRNA translation and expression.The optimal working dilution should be determined by the end user.
Storage Buffer:
20 mM Tris-HCl pH8.0, 100 mM NaCl, 1 mM DTT, 0.1 mM EDTA, 0.1% TritonX-100, 50% (v/v) Glycerol.