Human LILRB2/ILT-4/CD85d Recombinant Protein (85-430)

Product Code:
PSI-85-430

Supplier:
ProSci

Regulatory Status:
RUO

Target Species:
Human

Applications:

Enzyme-Linked Immunosorbent Assay (ELISA)
Immunogen
SDS-PAGE
Western Blot (WB)

Shipping:
RT

Storage:
Store at -20°C. Store the lyophilized protein at -20°C to -80 °C up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.

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Further Information

Application Note:

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity Test

Background:

Leukocyte immunoglobulin-like receptor subfamily B member 2 (LILRB2) is also known as CD85 antigen-like family member D (CD85d), Immunoglobulin-like transcript 4 (ILT-4), Monocyte / macrophage immunoglobulin-like receptor 10 (MIR-10), which is a member of the the subfamily B class of LIR receptors.Multiple transcript variants encoding different isoforms have been found for the ILT4 gene. ILT4 is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity.

Buffer:

Lyophilized from a 0.22 um filtered solution of PBS, pH 7.4.

NCBI Gene ID:

10288

Physical State:

Lyophilized

Predicted MW:

74.51 kDa

Protein Accession:

AAH36827.1

Source Species:

HEK293 cells

SwissProt:

Q8N423-1

Documents

Datasheet