ProSci

Human PBEF/Visfatin/NAMPT Recombinant Protein (85-122)

Product Code:
PSI-85-122
Product Group:
Recombinant Proteins
Supplier:
ProSci
Regulatory Status:
RUO
Target Species:
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunogen
  • SDS-PAGE
  • Western Blot (WB)
Product Type:
Enzymes
Shipping:
RT
Storage:
Store at -20°C. Store the lyophilized protein at -20°C to -80 °C up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
 

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This product comes from: United States.
Typical lead time: 14-21 working days.
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Further Information

Application Note:
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity Test
Background:
Pre-B cell colony enhancing factor (PBEF) was originally identified as a cytokine that potentiated the clonalexpansion and differentiation of pre-B cells, but it is also acknowledged to be the ubiquitous intracellularenzyme nicotinamide phosphoribosyltranferase (NAMPT) and the adipokine " visfatin " . PBEF is constitutivelyexpressed in the fetal membranes where its greatest expression is in the amnion. It has intracellular andextracellular forms. Most of the intracellular functions of PBEF are due to its role as a Nampt which can induceangiogenesis through upregulation of VEGF and VEGFR and secretion of MCP-1. Extracellular PBEF has beenshown to increase inflammatory cytokines, such as TNF- α , IL-1 β , IL-16, and TGF- β 1. PBEF also increases theproduction of IL-6, TNF- α , and IL-1 β in CD14+ monocyctes, macrophages, and dendritic cells, enhances theeffectiveness of T cells.
Buffer:
Lyophilized from a 0.2 um filtered solution of 20mM HEPES, 150mM NaCl, pH8.0.Contact us for customized product form or formulation.
NCBI Gene ID:
10135
Physical State:
Lyophilized
Predicted MW:
55.39 kDa
Protein Accession:
P43490
Source Species:
E. coli
SwissProt:
P43490

Documents