ProSci

Mouse Alkaline Phosphatase,Tissue-nonspecific Isozyme/ALPL Recombinant Protein (85-959)

Product Code:
PSI-85-959
Product Group:
Recombinant Proteins
Supplier:
ProSci
Regulatory Status:
RUO
Target Species:
Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunogen
  • SDS-PAGE
  • Western Blot (WB)
Product Type:
Enzymes
Shipping:
RT
Storage:
Store at -20°C. Store the lyophilized protein at -20°C to -80 °C up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
 

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Further Information

Application Note:
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity Test
Background:
Several distinct genes encode alkaline phosphatases (APs) in mice with different tissue-specific expression patterns. The Alpl gene, also known as Akp2, encodes the liver/bone/kidney isozyme, also known as the tissue-nonspecific AP (TNAP). The Alpl gene is a key regulator of bone mineralization in mice . A variety of mutations in the human ALPL gene leads to different forms of hypophosphatasia, characterized by poorly mineralized cartilage and bones . The native ALPL is a glycosylated homodimer attached to the membrane through a GPI-anchor.
Buffer:
Lyophilized from a 0.2 um filtered solution of 20mM HEPES, 150mM NaCl, 2mM MgSO4, 0.1mM ZnCl2,pH 7.5.
NCBI Gene ID:
11647
Physical State:
Lyophilized
Predicted MW:
54.26 KDa
Protein Accession:
NP_001274101.1
Source Species:
HEK293 cells
SwissProt:
P09242

Documents