ProSci

Mouse TNFRSF5/CD40 Recombinant Protein (85-388)

Product Code:
PSI-85-388
Product Group:
Recombinant Proteins
Supplier:
ProSci
Regulatory Status:
RUO
Target Species:
Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunogen
  • SDS-PAGE
  • Western Blot (WB)
Product Types:
  • CD Proteins
  • Receptors
Shipping:
RT
Storage:
Store at -20°C. Store the lyophilized protein at -20°C to -80 °C up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
 

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This product comes from: United States.
Typical lead time: 14-21 working days.
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Further Information

Application Note:
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity Test
Background:
CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins.plays an essential role in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation.CD40 is a costimulatory protein found on antigen presenting cells and is required for their activation, and is expressed in B cells, dendritic cells, macrophages, endothelial cells, and several tumor cell lines.Interaction of CD40 with its ligand, CD40L, leads to aggregation of CD40 molecules,which in turn interact with cytoplasmic components to initiate signaling pathways. Early studies on the CD40-CD40L system revealed its role in humoral immunity. Defects in CD40 result in hyper-IgM immunodeficiency type 3 (HIGM3).
Buffer:
Lyophilized from a 0.22 um filtered solution of PBS, pH 7.4.
NCBI Gene ID:
21939
Physical State:
Lyophilized
Predicted MW:
20.20 kDa
Protein Accession:
NP_035741.2
Source Species:
HEK293 cells
SwissProt:
P27512

Documents