ProSci

Phospho-Rac1/Cdc42-S71 Rabbit Recombinant Antibody (84-587)

Product Code:
PSI-84-587
Product Group:
Primary Antibodies
Supplier:
ProSci
Host Type:
Rabbit
Antibody Isotype:
IgG
Antibody Clonality:
Monoclonal
Regulatory Status:
RUO
Target Species:
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Shipping:
RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
 

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This product comes from: United States.
Typical lead time: 14-21 working days.
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Further Information

Application Note:
WB,1:500 - 1:2000|ELISA,Recommended starting concentration is 1 ug/mL. Please optimize the concentration based on your specific assay requirements.
Background:
The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20. [provided by RefSeq, Apr 2013]
Buffer:
Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Concentration:
Batch dependent
Conjugate:
Unconjugated
NCBI Gene ID:
998/5879
NCBI Symbol:
CDC42/RAC1
Physical State:
Liquid
Predicted MW:
24kDa
Protein Accession:
P60953/P63000
SwissProt:
P60953/P63000

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