ProSci

Rat B7-H1/PD-L1/CD274 Recombinant Protein (85-617)

Product Code:
PSI-85-617
Product Group:
Recombinant Proteins
Supplier:
ProSci
Regulatory Status:
RUO
Target Species:
Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunogen
  • SDS-PAGE
  • Western Blot (WB)
Product Types:
  • CD Proteins
  • Immune Checkpoint
Shipping:
RT
Storage:
Store at -20°C. Store the lyophilized protein at -20°C to -80 °C up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
 

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This product comes from: United States.
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Further Information

Application Note:
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity Test
Background:
This protein is an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation.
Buffer:
Lyophilized from a 0.22 um filtered solution of PBS, pH 7.4.
NCBI Gene ID:
499342
Physical State:
Lyophilized
Predicted MW:
25.90 kDa
Protein Accession:
NP_001178883.1
Source Species:
HEK293 cells
SwissProt:
D4AE25

Documents