ProSci

Rat IL-18 Recombinant Protein (85-909)

Product Code:
PSI-85-909
Product Group:
Recombinant Proteins
Supplier:
ProSci
Regulatory Status:
RUO
Target Species:
Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunogen
  • SDS-PAGE
  • Western Blot (WB)
Product Types:
  • Cytokines and Other Signalling
  • Interleukins
Shipping:
RT
Storage:
Store at -20°C. Store the lyophilized protein at -20°C to -80 °C up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
 

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This product comes from: United States.
Typical lead time: 14-21 working days.
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Further Information

Application Note:
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity Test
Background:
IL-18 ,Pro-inflammatory cytokine primarily involved in epithelial barrier repair, polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells and natural killer (NK) cells. Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore.
Buffer:
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
NCBI Gene ID:
29197
Physical State:
Lyophilized
Predicted MW:
18.96 kDa
Protein Accession:
NP_062038.1
Source Species:
HEK293 cells
SwissProt:
P97636-1

Documents