ProSci

SARS-CoV-2 (COVID-19) Spike L452R Antibody (Delta Variant)

Product Code:
PSI-9463
Product Group:
Primary Antibodies
Supplier:
ProSci
Host Type:
Rabbit
Antibody Isotype:
IgG
Antibody Clonality:
Polyclonal
Regulatory Status:
RUO
Target Species:
SARS-CoV-2
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Product Type:
Microbial and Virus Specific
Shipping:
RT
Storage:
Store at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
 

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This product comes from: United States.
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Further Information

Application Note:
WB: 1 ug/mL. Antibody validated: Western Blot in human samples. Anti-SARS-CoV-2 Spike L452R (Delta Variant) antibody specifically detects SARS-CoV-2 Delta Variant (B.1.617.2) Spike S1 protein, but not SARS-CoV-2 WT and other variant Spike S1 proteins by ELISA. All other applications and species not yet tested.
Background:
SARS-CoV-2 delta variant, a variant of concern (VOC), known as B.1.617.2, was detected in India in October of 2020. However, it rapidly spread all over of the world and now it is the dominant variant in the world, which account for more than 99% of the cases. This variant carries at least 13 mutations in spike protein across the sub lineages, including L452R, D614G, P681R and K417N, which can increase the affinity to the human ACE2 receptor. Enhanced transmission of the Delta variant was observed globally, which is at least 2.5 times more contagious as the other variants. The Delta variant affects the effectiveness of COVID19 vaccine and is resistant to neutralization to some extent.
Buffer:
SARS-CoV-2 Spike Delta Variant antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
Homology:
Predicted reactivity based on immunogen sequence: SARS-CoV Spike proteins: (77.8%)
NCBI Gene ID:
43740568
NCBI Name:
surface glycoprotein
NCBI Symbol:
S
Physical State:
Liquid
Protein Accession:
QHD43416
Purification:
Anti-SARS-CoV-2 Spike Delta Variant antibody is affinity chromatography purified via peptide column.
Specificity:
It can only detect SARS-CoV-2 Delta Variant (B.1.617.2) Spike S1 protein and does not cross-react with the spike protein of other variants.
SwissProt:
P0DTC2

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