ProSci

SHP1 Rabbit Recombinant Antibody (81-379)

Product Code:
PSI-81-379
Product Group:
Primary Antibodies
Supplier:
ProSci
Host Type:
Rabbit
Antibody Isotype:
IgG
Antibody Clonality:
Monoclonal
Regulatory Status:
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunofluorescence (IF)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Shipping:
RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
 

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This product comes from: United States.
Typical lead time: 14-21 working days.
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Further Information

Application Note:
WB,1:1000 - 1:2000|IF-P,1:100 - 1:800|IHC-P,1:200 - 1:2000|ELISA,Recommended starting concentration is 1 ug/mL. Please optimize the concentration based on your specific assay requirements.
Background:
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of this gene, which encode distinct isoforms, have been reported.
Buffer:
Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Concentration:
Batch dependent
Conjugate:
Unconjugated
NCBI Gene ID:
5777
NCBI Symbol:
PTPN6
Physical State:
Liquid
Predicted MW:
68kDa
Protein Accession:
P29350
SwissProt:
P29350

Documents