ProSci

Sorbitol Dehydrogenase Rabbit Recombinant Antibody (82-020)

Product Code:
PSI-82-020
Product Group:
Primary Antibodies
Supplier:
ProSci
Host Type:
Rabbit
Antibody Isotype:
IgG
Antibody Clonality:
Monoclonal
Regulatory Status:
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Product Type:
Enzymes
Shipping:
RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
 

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Further Information

Application Note:
WB,1:2000 - 1:20000|ELISA,Recommended starting concentration is 1 ug/mL. Please optimize the concentration based on your specific assay requirements.
Background:
Sorbitol dehydrogenase (SORD; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1; MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.
Buffer:
Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Concentration:
Batch dependent
Conjugate:
Unconjugated
NCBI Gene ID:
6652
NCBI Symbol:
SORD
Physical State:
Liquid
Predicted MW:
38kDa
Protein Accession:
Q00796
SwissProt:
Q00796

Documents