ProSci

T-bet/Tbx21 Rabbit Recombinant Antibody (83-133)

Product Code:
PSI-83-133
Product Group:
Primary Antibodies
Supplier:
ProSci
Host Type:
Rabbit
Antibody Isotype:
IgG
Antibody Clonality:
Monoclonal
Regulatory Status:
RUO
Target Species:
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Flow Cytometry
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Product Type:
Transcription & Translation Factors
Shipping:
RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
 

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Further Information

Application Note:
WB,1:1000 - 1:5000|IHC-P,1:200 - 1:800|FC (intra),1:500 - 1:1000|ELISA,Recommended starting concentration is 1 ug/mL. Please optimize the concentration based on your specific assay requirements.
Background:
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG). Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells.
Buffer:
Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Concentration:
Batch dependent
Conjugate:
Unconjugated
NCBI Gene ID:
30009
NCBI Symbol:
TBX21
Physical State:
Liquid
Predicted MW:
58kDa
Protein Accession:
Q9UL17
SwissProt:
Q9UL17

Documents