ProSci

TLR2 Rabbit Recombinant Antibody (81-391)

Product Code:
PSI-81-391
Product Group:
Primary Antibodies
Supplier:
ProSci
Host Type:
Rabbit
Antibody Isotype:
IgG
Antibody Clonality:
Monoclonal
Regulatory Status:
RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunocytochemistry (ICC)
  • Immunofluorescence (IF)
  • Western Blot (WB)
Shipping:
RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
 

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Further Information

Application Note:
WB,1:1000 - 1:2000|IF/ICC,1:100 - 1:400|IF-P,1:100 - 1:400|ELISA,Recommended starting concentration is 1 ug/mL. Please optimize the concentration based on your specific assay requirements.
Background:
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. This protein is a cell-surface protein that can form heterodimers with other TLR family members to recognize conserved molecules derived from microorganisms known as pathogen-associated molecular patterns (PAMPs). Activation of TLRs by PAMPs leads to an up-regulation of signaling pathways to modulate the host's inflammatory response. This gene is also thought to promote apoptosis in response to bacterial lipoproteins. This gene has been implicated in the pathogenesis of several autoimmune diseases. Alternative splicing results in multiple transcript variants.
Buffer:
Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Concentration:
Batch dependent
Conjugate:
Unconjugated
NCBI Gene ID:
7097
NCBI Symbol:
TLR2
Physical State:
Liquid
Predicted MW:
90kDa
Protein Accession:
O60603
SwissProt:
O60603

Documents