ProSci

TMEM41B (CT) Antibody

Product Code:
PSI-9565
Product Group:
Primary Antibodies
Supplier:
ProSci
Host Type:
Rabbit
Antibody Isotype:
IgG
Antibody Clonality:
Polyclonal
Regulatory Status:
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunofluorescence (IF)
  • Western Blot (WB)
Shipping:
RT
Storage:
Store at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
 

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Further Information

Application Note:
WB: 2 ug/mL; IF: 20 ug/mL. Antibody validated: Western Blot in mouse and rat samples; Immunofluorescence in human, mouse and rat samples. All other applications and species not yet tested.
Background:
TMEM41B Antibody: TMEM41B is required for autophagosome formation and participates in early stages of autophagosome biogenesis at the ER membrane probably via mobilization of neutral lipids from lipid droplets. TMRM41B is a critical host factor required for infection by human coronaviruses SARS-CoV-2, HCoV-OC43, HCoV-NL63, and HCoV-229E, as well as all flaviviruses tested such as Zika virus and Yellow fever virus. It is required post-entry of the virus to facilitate the ER membrane remodeling necessary to form replication organelles.
Buffer:
TMEM41B Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
Homology:
Predicted species reactivity based on immunogen sequence: Bovine (100%); Chicken (100%); Chimpanzee (100%).
NCBI Gene ID:
440026
NCBI Name:
transmembrane protein 41B
NCBI Symbol:
TMEM41B
Physical State:
Liquid
Predicted MW:
Predicted: 33kD Observed: 33 kD
Protein Accession:
Q5BJD5
Purification:
TMEM41B Antibody is affinity chromatography purified via peptide column.
SwissProt:
Q5BJD5

Documents