ProSci

TNF-a Rabbit Recombinant Antibody (82-145)

Product Code:
PSI-82-145
Product Group:
Primary Antibodies
Supplier:
ProSci
Host Type:
Rabbit
Antibody Isotype:
IgG
Antibody Clonality:
Monoclonal
Regulatory Status:
RUO
Target Species:
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Product Types:
  • Growth Factors
  • TNFs
Shipping:
RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
 

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This product comes from: United States.
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Further Information

Application Note:
WB,1:10000 - 1:40000|ELISA,Recommended starting concentration is 1 ug/mL. Please optimize the concentration based on your specific assay requirements.
Background:
This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, psoriasis, rheumatoid arthritis ankylosing spondylitis, tuberculosis, autosomal dominant polycystic kidney disease, and cancer. Mutations in this gene affect susceptibility to cerebral malaria, septic shock, and Alzheimer disease. Knockout studies in mice also suggested the neuroprotective function of this cytokine.
Buffer:
Buffer: PBS with 0.09% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Concentration:
Batch dependent
Conjugate:
Unconjugated
NCBI Gene ID:
7124
NCBI Symbol:
TNF
Physical State:
Liquid
Predicted MW:
26kDa
Protein Accession:
P01375
SwissProt:
P01375

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