ProSci

Trophinin Antibody

Product Code:
PSI-8245
Product Group:
Primary Antibodies
Supplier:
ProSci
Host Type:
Rabbit
Antibody Isotype:
IgG
Antibody Clonality:
Polyclonal
Regulatory Status:
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunofluorescence (IF)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Shipping:
RT
Storage:
Store at 4°C for three months and -20°C, stable for up to one year.
 

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Further Information

Application Note:
Trophinin antibody can be used for detection of Trophinin by Western blot at 1 - 2 ug/ml. Antibody can also be used for immunohistochemistry at 10 ug/ml. Antibody validated: Western Blot in rat samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
Background:
Trophinin, also known as TRO or MAGED3, is an apical cell adhesion molecule that is implicated in the initial attachment during the process of embryo implantation and functions by mediating cell adhesion between trophoblastic and endometrial epithelial cells (1,2). Trophinin is a membrane protein expressed in chorionic villi trophoblasts and in maternal endometrial epithelial cells in an implantation-dependent manner and interacts with Bystin and Tastin, facilitating cell adhesion and embryo implantation (3,4). The induction of Trophinin expression may be a useful method for improving implantation rates and can be a potential diagnostic factor and biomarker for human cancer (4,5).
Buffer:
Trophinin antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
NCBI Gene ID:
7216
NCBI Name:
trophinin
NCBI Symbol:
TRO
Physical State:
Liquid
Predicted MW:
Predicted: 78, 157 kDa Observed: 94 kDa
Protein Accession:
NP_001034794
Purification:
Trophinin antibody is affinity chromatography purified via peptide column.
Specificity:
Trophinin antibody is human, mouse and rat reactive. Multiple isoforms of Trophinin are known to exist.
SwissProt:
Q12816

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