AdipoGen Life Sciences

anti-Irisin pAb (IN102) (Biotin)

Product Code:
AG-25B-0027B
Product Group:
Primary Antibodies
Host Type:
Rabbit
Antibody Clonality:
Polyclonal
Regulatory Status:
RUO
Target Species:
  • Bovine (Cattle)
  • Human
  • Monkey
  • Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Product Type:
Tagged
Shipping:
Blue Ice
Storage:
Short term: +4°C. Long term: -20°C
 

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Further Information

Alternate Names/Synonyms:
Fibronectin Type III Domain-containing Protein 5 (cleaved); Fibronectin Type III Repeat-containing Protein 2 (cleaved); FNDC5 (cleaved)
Concentration:
0.5mg/ml
EClass:
32160000
Form (Short):
liquid
Formulation:
Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
Handling Advice:
After opening, prepare aliquots and store at -20°C.Avoid freeze/thaw cycles.
Immunogen:
Recombinant irisin.
Labels - Conjugates:
Biotin
Long Description:
Polyclonal Antibody. Recognizes human, mouse, rat, monkey Irisin and FNDC5. Detects endogenous mouse and human Irisin [Lit: 1-2]. Source: Rabbit. Applications: ELISA, WB. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells (beige cells have a gene expression pattern distinct from either white or brown fat and are preferentially sensitive to the polypeptide hormone Irisin). Irisin is cleaved from the type I membrane protein FNDC5 and improves systemic metabolism by increasing energy expenditure.
NCBI, Uniprot Number:
Q8NAU1
Package Type:
Plastic Vial
Product Description:
Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells (beige cells have a gene expression pattern distinct from either white or brown fat and are preferentially sensitive to the polypeptide hormone Irisin). Irisin is cleaved from the type I membrane protein FNDC5 and improves systemic metabolism by increasing energy expenditure.
Source / Host:
Synthetic.
Specificity:
Recognizes human, mouse, rat, monkey Irisin and FNDC5. Detects endogenous mouse and human Irisin [Lit: 1-2].
Transportation:
Non-hazardous
UNSPSC Category:
Primary Antibody Conjugates
UNSPSC Number:
12352203
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C.

References

Exercise Induces Hippocampal BDNF through a PGC-1alpha/FNDC5 Pathway: C.D. Wrann, et al.; Cell Metab. 18, 649 (2013) | Detection and quantitation of circulating human irisin by tandem mass spectrometry: M.P. Jedrychowski, et al.; Cell Metab. 22, 734 (2015)