Chemodex

Tris(hydroxymethyl) aminomethane

Product Code:
CDX-T0244
Product Group:
Biological Buffers
Supplier:
Chemodex
Regulatory Status:
RUO
Shipping:
Ambient
Storage:
Short term: +20°C. Long term: +20°C
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Chemical Structure
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Chemical Structure

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This product comes from: Switzerland.
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Further Information

Alternate Names/Synonyms:
2-Amino-2-(hydroxymethyl)-1,3-propanediol; THAM; Tris base; Trometamol
Appearance:
White to off-white powder.
CAS:
77-86-1
EClass:
32160000
Form (Short):
solid
Handling Advice:
Protect from moisture.
InChi:
InChI=1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2
InChiKey:
LENZDBCJOHFCAS-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 77-86-1. Formula: C4H11NO3. MW: 121.14. Synthetic. A high quality buffer used in the range of physiological pH 7-9. Widely used as a biological buffer or as a component of buffer formulations. Tris has a pKa of 8.06 and is very useful in the biology and biochemistry lab because it has buffering capabilities in the range of the typical physiological pH of most living organisms (pH 7.0-9.0). Tris has been reported to interfere with the activity of a number of enzymes, it should therefore be used carefully when studying proteins.
MDL:
MFCD00004679
Molecular Formula:
C4H11NO3
Molecular Weight:
121.14
Package Type:
Vial
Product Description:
A high quality buffer used in the range of physiological pH 7-9. Widely used as a biological buffer or as a component of buffer formulations. Tris has a pKa of 8.06 and is very useful in the biology and biochemistry lab because it has buffering capabilities in the range of the typical physiological pH of most living organisms (pH 7.0-9.0). Tris has been reported to interfere with the activity of a number of enzymes, it should therefore be used carefully when studying proteins.
Purity:
>99%
SMILES:
NC(CO)(CO)CO
Solubility Chemicals:
Soluble in water (550mg/ml), methanol (26mg/ml), ethanol (14mg/ml), DMF (14mg/ml) or acetone (2mg/ml).
Source / Host:
Synthetic.
Transportation:
Non-hazardous
UNSPSC Category:
Biological Buffers
UNSPSC Number:
12161700
Use & Stability:
Stable for at least 2 years after receipt when stored at RT.

References

(1) R.H. Kallet, et al.; Am. J. Respir. Crit. Care Med. 161, 1149 (2000) | (2) W.T. Desmarais, et al.; Structure 10, 1063 (2002) | (3) Z. Ghalanbor, et al.; Protein Pept. Lett. 15, 212 (2008) | (4) J. Sambrook, & D.W. Russell; Molecular Cloning: A Laboratory Manual (2012)