Collagen Hybridizing Peptide, 5-FAM Conjugate (F-CHP)
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| Code | Size | Price |
|---|
| 3H-FLU60 | 60 ug | £248.00 |
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This product comes from: United States.
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Typical lead time: 14-21 working days.
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- Further Information
- Documents
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Further Information
Conjugate:
Single fluorescein tag per peptide
Molecular Mass(KD):
2952.01 g/mol
Product information:
The collagen hybridizing peptide (CHP) is a novel and unique peptide that specifically binds unfolded collagen chains, both?in vitro?and?in vivo.[1,2,3]?By sharing the Gly-X-Y repeating sequence of natural collagen, CHP has a strong capability to hybridize with denatured collagen chains by reforming the triple helical structure, in a fashion similar to DNA fragments annealing to complementary DNA strands. CHP is extremely specific: it has negligible affinity to intact collagen molecules due to lack of binding sites, and it is inert towards non-specific binding because of its neutral and hydrophilic nature.
Purity:
95%
Documents
References
- https://doi.org/10.1152/ajpheart.00331.2024
- JOR Spine. 2020 Sep 21;3(4):e1126. doi: 10.1002/jsp2.1126. eCollection 2020 Dec.Read more here.
- J Am Chem Soc. 2023 May 24;145(20):10901-10916. doi: 10.1021/jacs.3c00713. Epub 2023 May 9.Read more here.
- Mahara, Atsushi, et al. "Improving hemocompatibility of decellularized vascular tissue by structural modification of collagen fiber."?International Journal of Biological Macromolecules?269 (2024): 132040.Read more here.
- Acta Biomater. 2018 Feb;67:307-318. doi: 10.1016/j.actbio.2017.11.052. Epub 2017 Dec 8.Read more here.
- J Mech Behav Biomed Mater. 2019 Sep;97:254-271. doi: 10.1016/j.jmbbm.2019.04.022. Epub 2019 May 4.Read more here.
- J Mech Behav Biomed Mater. 2020 Sep;109:103834. doi: 10.1016/j.jmbbm.2020.103834. Epub 2020 May 1.Read more here.
- J Pediatr Gastroenterol Nutr. 2020 Jan;70(1):87-92. doi: 10.1097/MPG.0000000000002505.Read more here.
- Yang, Guang et al. ?Fabrication of centimeter-sized 3D constructs with patterned endothelial cells through assembly of cell-laden microbeads as a potential bone graft.??Acta biomaterialia?vol. 121 (2021): 204-213. doi:10.1016/j.actbio.2020.11.040Read more here.
- Yoon, Hyejin, et al. "Collagen structures of demineralized bone paper direct mineral metabolism."?JBMR Plus?(2024): ziae080.Read more here.
- J Mech Behav Biomed Mater. 2022 Jul;131:105220. doi: 10.1016/j.jmbbm.2022.105220. Epub 2022 Apr 5.Read more here.
- Hortells, Luis et al. ?A specialized population of Periostin-expressing cardiac fibroblasts contributes to postnatal cardiomyocyte maturation and innervation.??Proceedings of the National Academy of Sciences of the United States of America?vol. 117,35 (2020): 21469-21479. doi:10.1073/pnas.2009119117Read more here.
- Hortells, Luis et al. ?Periostin-expressing Schwann cells and endoneurial cardiac fibroblasts contribute to sympathetic nerve fasciculation after birth.??Journal of molecular and cellular cardiology?vol. 154 (2021): 124-136. doi:10.1016/j.yjmcc.2021.02.001Read more here.
- Widiapradja, Alexander et al. ?Replacement of Lost Substance P Reduces Fibrosis in the Diabetic Heart by Preventing Adverse Fibroblast and Macrophage Phenotype Changes.??Cells?vol. 10,10 2659. 5 Oct. 2021, doi:10.3390/cells10102659Read more here.
- Steijns, Felke et al. ?Spontaneous Right Ventricular Pseudoaneurysms and Increased Arrhythmogenicity in a Mouse Model of Marfan Syndrome.??International journal of molecular sciences?vol. 21,19 7024. 24 Sep. 2020, doi:10.3390/ijms21197024Read more here.