Collagen Hybridizing Peptide, Biotin Conjugate (B-CHP)
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| Code | Size | Price |
|---|
| 3H-BIO60 | 60 ug | £248.00 |
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This product comes from: United States.
Typical lead time: 14-21 working days.
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Typical lead time: 14-21 working days.
Contact us for more accurate information.
- Further Information
- Documents
- References
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Further Information
Conjugate:
Single biotin tag per peptide
Molecular Mass(KD):
2762.01 g/mol
Product information:
The collagen hybridizing peptide (CHP) is a novel and unique peptide that specifically binds unfolded collagen chains, both?in vitro?and?in vivo.[1,2,3]?By sharing the Gly-X-Y repeating sequence of natural collagen, CHP has a strong capability to hybridize with denatured collagen chains by reforming the triple helical structure, in a fashion similar to DNA fragments annealing to complementary DNA strands. CHP is extremely specific: it has negligible affinity to intact collagen molecules due to lack of binding sites, and it is inert towards non-specific binding because of its neutral and hydrophilic nature.
Purity:
95%
Documents
References
- J Cell Sci. 2020 Dec 11;133(23):jcs248278. doi: 10.1242/jcs.248278.Read more here.
- Horn, Lucas A et al. ?Remodeling the tumor microenvironment via blockade of LAIR-1 and TGF-? signaling enables PD-L1-mediated tumor eradication.??The Journal of clinical investigation?vol. 132,8 (2022): e155148. doi:10.1172/JCI155148Read more here.
- JOR Spine. 2020 Sep 21;3(4):e1126. doi: 10.1002/jsp2.1126. eCollection 2020 Dec.Read more here.
- J Am Chem Soc. 2023 May 24;145(20):10901-10916. doi: 10.1021/jacs.3c00713. Epub 2023 May 9.Read more here.
- Int J Mol Sci. 2022 Apr 12;23(8):4245. doi: 10.3390/ijms23084245.Read more here.
- Feng, Xiaotian et al. ?Apical expansion of calvarial osteoblasts and suture patency is dependent on graded fibronectin cues.??bioRxiv : the preprint server for biology?2023.01.16.524278. 16 Jan. 2023, doi:10.1101/2023.01.16.524278. Preprint.Read more here.
- Aging Cancer. 2022 Jun;3(2):116-129. doi: 10.1002/aac2.12049. Epub 2022 Apr 19.Read more here.
- Jin, Hyo-Eon et al. ?Collagen mimetic peptide engineered M13 bacteriophage for collagen targeting and imaging in cancer.??Biomaterials?vol. 35,33 (2014): 9236-45. doi:10.1016/j.biomaterials.2014.07.044Read more here.
- Vagnozzi, Ronald J et al. ?An acute immune response underlies the benefit of cardiac stem?cell therapy.??Nature?vol. 577,7790 (2020): 405-409. doi:10.1038/s41586-019-1802-2Read more here.
- Wang, William Y et al. ?Dynamic Endothelial Stalk Cell-Matrix Interactions Regulate Angiogenic Sprout Diameter.??Frontiers in bioengineering and biotechnology?vol. 9 620128. 19 Mar. 2021, doi:10.3389/fbioe.2021.620128Read more here.
- Lee, Soo Jung et al. ?A midposition NOTCH3 truncation in inherited cerebral small vessel disease may affect the protein interactome.??The Journal of biological chemistry?vol. 299,1 (2023): 102772. doi:10.1016/j.jbc.2022.102772Read more here.
- Filiberti, Adrian et al. ?An intact complement system dampens cornea inflammation during acute primary HSV-1 infection.??Scientific reports?vol. 11,1 10247. 13 May. 2021, doi:10.1038/s41598-021-89818-9Read more here.
- Filiberti, Adrian et al. ?Loss of Osteopontin Expression Reduces HSV-1-Induced Corneal Opacity.??Investigative ophthalmology & visual science?vol. 61,10 (2020): 24. doi:10.1167/iovs.61.10.24Read more here.
- Viiklepp, Kristina et al. ?C1r Upregulates Production of Matrix Metalloproteinase-13 and Promotes Invasion of Cutaneous Squamous Cell Carcinoma.??The Journal of investigative dermatology?vol. 142,5 (2022): 1478-1488.e9. doi:10.1016/j.jid.2021.10.008Read more here.
- Zhang, Xiaojie et al. ?Hydrolysis of a second Asp-Pro site at the N-terminus of NOTCH3 in inherited vascular dementia.??Scientific reports?vol. 11,1 17246. 26 Aug. 2021, doi:10.1038/s41598-021-96679-9Read more here.