Polydatin
Product Code:
TAR-T3427
TAR-T3427
Regulatory Status:
RUO
RUO
Shipping:
cool pack
cool pack
Storage:
-20℃
-20℃
No additional charges, what you see is what you pay! *
| Code | Size | Price |
|---|
| TAR-T3427-50mg | 50mg | £82.00 |
Quantity:
| TAR-T3427-100mg | 100mg | £102.00 |
Quantity:
| TAR-T3427-500mg | 500mg | £165.00 |
Quantity:
Prices exclude any Taxes / VAT
Stay in control of your spending. These prices have no additional charges to UK mainland customers, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: Austria.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
- Further Information
- Documents
- References
- Show All
Further Information
Bioactivity:
Polydatin, the glycoside of Resveratrol, is originally isolated from the Chinese herb Polygonum cuspidatum. The compound can inhibit platelet aggregation and elevate the ratios of LDL-C/HDL-C and TC/HDL-C. In the myocardial cell, white blood cell, vascular smooth muscle cell, and endothelial cell, Polydatin can inhibit ICAM-1 expression, elevate Ca2+, weaken white blood cell-endothelial cell adhesion, and activate KATP channels.
CAS:
27208-80-6
Formula:
C21H24O7
Molecular Weight:
388.416
Pathway:
Apoptosis; NF-κb; Autophagy
Purity:
0.9883
SMILES:
OC[C@H]1O[C@@H](Cc2cc(O)cc(C=Cc3ccc(O)cc3)c2)[C@H](O)[C@@H](O)[C@@H]1O
Target:
Apoptosis; Mitophagy; NF-κB; Autophagy
References
Guan S Y, Zhang K, Wang X S, et al. Anxiolytic effects of polydatin through the blockade of neuroinflammation in a chronic pain mouse model[J]. Molecular Pain. 2020, 16: 1744806919900717.
Cheng Y, et al. Involvement of cell adhesion molecules in polydatin protection of brain tissues from ischemia-reperfusion injury. Brain Res. 2006 Sep 19;1110(1):193-200.
Wang HL, et al. Synergistic effects of Polydatin and Vitamin C in Inhibiting Cardiotoxicity induced by Doxorubicin in rats. Fundam Clin Pharmacol. 2016 Nov 28. [Epub ahead of print]
Geng W, Guo X, Zhang L, et al. Resveratrol inhibits proliferation, migration and invasion of multiple myeloma cells via NEAT1-mediated Wnt/?-catenin signaling pathway[J]. Biomedicine & Pharmacotherapy. 2018 Nov;107:484-494.
Guan S Y, Zhang K, Wang X S, et al. Anxiolytic effects of polydatin through the blockade of neuroinflammation in a chronic pain mouse model. Molecular Pain. 2020, 16: 1744806919900717
Geng W, Guo X, Zhang L, et al. Resveratrol inhibits proliferation, migration and invasion of multiple myeloma cells via NEAT1-mediated Wnt/?-catenin signaling pathway Resveratrol inhibits proliferation, migration and invasion of multiple myeloma cells via NEAT1-mediated Wnt/?-catenin signaling pathway. Biomedicine & Pharmacotherapy. 2018 Nov;107:484-494.
Polydatin ameliorates Staphylococcus aureus- induced mastitis in mice via inhibiting TLR2- mediated activation of the p38 MAPK/NF-?B pathway[J]. Acta Pharmacol Sin, 2017(38):222.