TargetMol

Cotransin

Product Code:
 
TAR-TP2563
Product Group:
 
Peptides
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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This product comes from: Austria.
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Further Information

Bioactivity:
Cotransin, a Sec61 translocation inhibitor, selectively prevents the stable insertion of certain nascent chains into the Sec61 translocation channel, exhibiting signal-sequence discrimination. This compound also inhibits the expression of VCAM-1 and p-selectin proteins by blocking their co-translational translocation across endoplasmic reticulum (ER) membranes (IC 50 =0.5-5 uM). Cotransin's role extends to potential applications in inflammation and immunity research [1] [2].
CAS Number:
863753-73-5
Formula:
C42H68N6O8
Molecular Weight:
785.02
Purity:
98%
SMILES:
C([C@@H]1N(C)C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)NC(=O)[C@@H](C)OC(=O)[C@H](C)N(C)C(=O)[C@H](CC(C)C)NC1=O)C2=CC=CC=C2

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