AdipoGen Life Sciences

CD137L Soluble (mouse) (rec.)

Product Code:
 
AG-40A-0020Y
Product Group:
 
Recombinant Proteins
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Shipping:
 
Blue Ice
Storage:
 
Short term: +4°C. Long term: -20°C
1 / 1
mCD137L-FLAG? binding to CD137 transfected cells.HEK 293 cells were transiently transfected with a construct encoding full-length mouse CD137. At 48hrs after transfection, the transfectants were incubated with 0.5 or 5?g/ml CD137L, Sol
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mCD137L-FLAG? binding to CD137 transfected cells.HEK 293 cells were transiently transfected with a construct encoding full-length mouse CD137. At 48hrs after transfection, the transfectants were incubated with 0.5 or 5?g/ml CD137L, Sol

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AG-40A-0020Y-C05050 ug£301.00
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Further Information

Alternate Names/Synonyms:
4-1BBL; TNFSF9
EClass:
32160000
Endotoxin:
<0.01EU/µg purified protein (LAL test; Lonza).
Form (Short):
solid
Formulation:
Lyophilized. Contains PBS.
Handling Advice:
After reconstitution, prepare aliquots and store at -20°C.Avoid freeze/thaw cycles.Centrifuge lyophilized vial before opening and reconstitution.PBS containing at least 0.1% BSA should be used for further dilutions.
Long Description:
Protein. The extracellular domain of mouse CD137L (aa 104-309) is fused at the N-terminus to a FLAG®-tag. Source: HEK 293 cells. Endotoxin content: <0.01EU/µg purified protein (LAL test; Lonza). Lyophilized. Contains PBS. Binds to mouse CD137. Purity: >95% (SDS-PAGE). The CD137 ligand (CD137L; 4-1BBL) is a member of the tumor necrosis factor (TNF) family. CD137L is a type II, transmembrane protein found on activated macrophages, dendritic cells and mature B cells. The interaction with its receptor 4-1BB induces recruitment of TNF receptor-associated factor 1 (TRAF1) and TRAF2 and interaction with the kinase p56lck. CD137 and CD137L have been reported to be involved in tumor rejection, apoptosis, anti-viral immunity, diabetes, in T and B cell co-stimulation and modulation of the immune response.
Molecular Weight:
~40kDa (SDS-PAGE)
NCBI, Uniprot Number:
P41274
Package Type:
Plastic Vial
Product Description:
The CD137 ligand (CD137L; 4-1BBL) is a member of the tumor necrosis factor (TNF) family. CD137L is a type II, transmembrane protein found on activated macrophages, dendritic cells and mature B cells. The interaction with its receptor 4-1BB induces recruitment of TNF receptor-associated factor 1 (TRAF1) and TRAF2 and interaction with the kinase p56lck. CD137 and CD137L have been reported to be involved in tumor rejection, apoptosis, anti-viral immunity, diabetes, in T and B cell co-stimulation and modulation of the immune response.
Purity:
>95% (SDS-PAGE)
Sequence:
The extracellular domain of mouse CD137L (aa 104-309) is fused at the N-terminus to a FLAG®-tag.
Source / Host:
HEK 293 cells
Specificity:
Binds to mouse CD137.
TAGs:
FLAG
Transportation:
Non-hazardous
UNSPSC Category:
Other Proteins
UNSPSC Number:
12352202
Use & Stability:
Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.