Corynesidone A

AdipoGen Life Sciences
Product Code: AG-CN2-0496
CodeSizePrice
AG-CN2-0496-M0011 mg£180.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
Ambient
Storage:
-20°C

Images

1 / 1
Chemical Structure

Chemical Structure

Further Information

Alternate Names/Synonyms:
3,8-Dihydroxy-1,6-dimethyl-11H-dibenzo[b,e][1,4]dioxepin-11-one; 2-Deoxycorynesidone C
Appearance:
White to off-white solid.
CAS:
1159583-61-5
EClass:
32160000
Form (Short):
solid
Handling Advice:
Keep cool and dry.
InChi:
InChI=1S/C15H12O5/c1-7-3-9(16)5-11-13(7)15(18)20-12-6-10(17)4-8(2)14(12)19-11/h3-6,16-17H,1-2H3
InChiKey:
KCAVPBLHZJMMLN-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 1159583-61-5. Formula: C15H12O5. MW: 272.3. Isolated from Corynespora sp. Potent antioxidant. Reactive oxygen species (ROS) and reactive nitrogen species (RNS) scavenger. Anti-cancer and anti-inflammatory compound. Aromatase activity inhibitor. Moderate cytotoxic against selected cancer cell lines.
MDL:
N/A
Molecular Formula:
C15H12O5
Molecular Weight:
272.3
Package Type:
Vial
Product Description:
Potent antioxidant. Reactive oxygen species (ROS) and reactive nitrogen species (RNS) scavenger. Anti-cancer and anti-inflammatory compound. Aromatase activity inhibitor. Moderate cytotoxic against selected cancer cell lines.
Purity:
>98% (HPLC)
SMILES:
OC1=CC2=C(OC(C=C(O)C=C3C)=C3C(O2)=O)C(C)=C1
Solubility Chemicals:
Soluble in DMSO, ethanol or methanol.
Source / Host:
Isolated from Corynespora sp.
Transportation:
Non-hazardous
UNSPSC Category:
Natural Products/Extracts
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.

References

Aromatase inhibitory, radical scavenging, and antioxidant activities of depsidones and diaryl ethers from the endophytic fungus Corynespora cassiicola L36: P. Chomcheon, et al.; Phytochem. 70, 407 (2009) | Natural compounds with aromatase inhibitory activity - An update: M.J. Balunas & A.D. Kinghorn; Planta Med. 76, 1087 (2010) | Inhibition of inflammatory mediators and reactive oxygen and nitrogen species by some depsidones and diaryl ether derivatives isolated from Corynespora cassiicola, an endophytic fungus of Gongronema latifolium leaves: F.B. Okoye, et al.; Immunopharmacol. Immunotoxicol. 35, 662 (2013) | Naphthalenones and depsidones from a sponge-derived strain of the fungus Corynespora cassiicola: D.L. Zhao, et al.; Molecules 21, 160 (2016)