Elabscience

PE Anti-Human CD8a Antibody[OKT-8]

Product Code:
 
E-AB-F1110D
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Mouse
Antibody Isotype:
 
Mouse IgG2a, κ
Antibody Clone:
 
OKT-8
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Flow Cytometry
Shipping:
 
Ice packs
Storage:
 
Store at 2-8°C and protected from prolonged exposure to light. Do not freeze.
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Human peripheral blood lymphocytes are stained with PE Anti-Human CD8a Antibody (filled gray histogram). Unstained lymphocytes (empty black histogram) are used as control.
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Human peripheral blood lymphocytes are stained with PE Anti-Human CD8a Antibody (filled gray histogram). Unstained lymphocytes (empty black histogram) are used as control.

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CodeSizePrice
E-AB-F1110D-20Tests20Tests£90.00
Quantity:
E-AB-F1110D-100Tests100Tests£116.00
Quantity:
E-AB-F1110D-100Testsx2100Testsx2£145.00
Quantity:
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This product comes from: China.
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Further Information

Abbreviation:
CD8
Background:
CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.
Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Concentration:
5 uL/Test
Conjugation:
PE
GeneID:
925
Target Synonym:
T-cell surface glycoprotein CD8 alpha chain;CD8A;T-lymphocyte differentiation antigen T8/Leu-2;MAL;
UNIProt ID:
P01732
Usage:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 uL of antibody per test (million cells in 100 uL staining volume or per 100 uL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

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