Chemodex

1,1'-Dibutyl-3,3,3',3'-tetramethyl indocarbocyanine iodide

Product Code:
 
CDX-D0224
Product Group:
 
Dyes, Stains, and Probes
Supplier:
 
Chemodex
Regulatory Status:
 
RUO
Shipping:
 
Ambient
Storage:
 
Short term: +4°C. Long term: -20°C
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Chemical Structure
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Chemical Structure

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CDX-D0224-M05050 mg£116.00
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CDX-D0224-M100100 mg£191.00
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CDX-D0224-M250250 mg£371.00
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  • Further Information
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Further Information

Appearance:
Violett crystalline solid.
CAS:
132752-00-2
Description:
DiIC4(3) is a fluorescent carbocyanine dye with butyl chains widely used for membrane staining due to its hydrophobic nature, which helps it intercalate well into lipid bilayers. Carbocyanine dyes are unique organic molecules that contain a conjugated electron-deficient system between two heterocyclic nitrogen atoms that provides characteristically long absorption and emission wavelengths. It can be used for cell tracking as it is stably retained in membranes and in fixed tissue slices for anterograde and retrograde tracing. Spectral Data: Excitation max: ~550-555nm, Emission max: ~565-570nm (accord. Lit). Also used as intermediate for the synthesis of selective protein arginine methyltransferases (PRMT) inhibitors. Intermediate for the synthesis of fluorescent probes.
EClass:
32160000
Form:
solid
GHS Symbol:
GHS07
Handling Advice:
Keep under inert gas. Protect from light and oxygen.
Hazards:
H315-H319-H335
InChi:
InChI=1S/C31H41N2.HI/c1-7-9-22-32-26-18-13-11-16-24(26)30(3,4)28(32)20-15-21-29-31(5,6)25-17-12-14-19-27(25)33(29)23-10-8-2;/h11-21H,7-10,22-23H2,1-6H3;1H/q+1;/p-1
InChiKey:
CVTQMCMIKOZBTI-UHFFFAOYSA-M
MDL:
MFCD01073652
Molecular Formula:
C31H41N2 . I
Molecular Weight:
568.58
Package Type:
Vial
Precautions:
P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362-P403+P233-P501
Purity:
>98% (HPLC)
Signal word:
Warning
SMILES:
CCCCN\1C2=CC=CC=C2C(/C1=C\C=C\C3=[N+](C4=CC=CC=C4C3(C)C)CCCC)(C)C.[I-]
Solubility Chemicals:
Soluble in DMSO or methanol.
Source / Host:
Synthetic
Transportation:
Non-hazardous
UNSPSC Number:
41105331
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.

Documents

References

(1) G. Suaerwein & G.B. Schuster; J. Phys. Chem. 95, 1903 (1991) | (2) G. Beckford, et al.; Talanta 92, 45 (2012) | (3) S.H. Sinha, et al.; Eur. J. Med. Chem. 54, 647 (2012) | (4) H. Hu, et al.; J. Med. Chem. 58, 1228 (2015) | (5) M. Matsui, et al.; Tetrahedron 71, 3528 (2015)