Chemodex

Gentamicin sulfate

Product Code:
 
CDX-G0050
Product Group:
 
Other Biochemicals
Supplier:
 
Chemodex
Regulatory Status:
 
RUO
Shipping:
 
Ambient
Storage:
 
Short term: +20°C. Long term: +4°C
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Chemical Structure

Chemical Structure

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CDX-G0050-G01010 g£255.00
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This product comes from: Switzerland.
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  • Further Information
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Further Information

Appearance:
White to off-white powder.
CAS:
1405-41-0
Description:
Gentamicin sulfate is a broad-spectrum aminoglycoside antibiotic used to treat a wide range of bacterial infections. It is antibacterial against Gram-negative aerobic bacteria, Gram-positive bacteria and mycoplasmas. Gentamicin sulfate is a protein synthesis inhibitor. It causes codon misreading by binding to the 30S ribosomal subunit, blocking the translocation of peptidyl-tRNA from the acceptor site to the donor site. Gentamicin sulfate is used as a selection agent (gentamicin-resistance gene) in molecular biology applications. It is a broad-spectrum cell culture antibiotic that is nontoxic to viruses and mammalian cells at antibacterial and antimycoplasmal concentrations. Due to its extended stability and slow development of bacterial resistance, it is a useful antibiotic in long-term virus und tissue culture studies.
EClass:
32160000
Form:
solid
GHS Symbol:
GHS07
Handling Advice:
Keep under inert gas. Protect from light and oxygen.
Hazards:
H317
InChiKey:
RDEIXVOBVLKYNT-HDZPSJEVSA-N
MDL:
MFCD00270181
Package Type:
Vial
Precautions:
P280
Signal word:
Warning
SMILES:
O=S(O)(O)=O.O[C@]1(C)[C@@H]([C@@H](O)[C@@H](O[C@@H]2[C@@H](O)[C@H](O[C@H]3O[C@@](CC[C@H]3N)([C@@H](C)NC)[H])[C@@H](N)C[C@H]2N)OC1)NC.O[C@]4(C)[C@@H]([C@@H](O)[C@@H](O[C@@H]5[C@@H](O)[C@H](O[C@H]6O[C@@](CC[C@H]6N)([C@@H](C)N)[H])[C@@H](N)C[C@H]5N)OC4)NC.O[
Solubility Chemicals:
Soluble in water (50 mg/ml).
Source / Host:
Microbial
Transportation:
Non-hazardous
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at +4°C.

Documents

References

(1) M. Finland; Med. Times 97, 161 (1969) (Review) | (2) R.E. Hancock; J. Antimicrob. Chemother. 8, 249 (1981) (Review) | (3) E. Hancock; J. Antimicrob. Chemother. 8, 429 (1981) (Review) | (4) N.L. Martin & T.J. Beveridge; Antimicrob. Agents Chemother. 29, 1079 (1986) | (5) J.P. Montenez, et al.; Toxicol. Lett. 73, 201 (1994) | (6) F.C. Luft; J. Mol. Med. 80, 543 (2002) (Review) | (7) Y. Quiros, et al.; Toxicol. Sci. 119, 245 (2011) (Review)