Chemodex

1-Pyrenebutanoic acid hydrazide

Product Code:
 
CDX-P0049
Product Group:
 
Dyes, Stains, and Probes
Supplier:
 
Chemodex
Regulatory Status:
 
RUO
Shipping:
 
Ambient
Storage:
 
Short term: +20°C. Long term: +20°C
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Chemical Structure
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Chemical Structure

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CDX-P0049-M100100 mg£203.00
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CDX-P0049-M250250 mg£383.00
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CDX-P0049-G0011 g£1,200.00
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This product comes from: Switzerland.
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  • Further Information
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Further Information

Appearance:
White to off-white powder.
CAS:
55486-13-0
Description:
1-Pyrenebutanoic acid hydrazide (PBH) is a fluorescent labeling reagent commonly used in biochemistry and molecular biology. Spectral Data: lambdaex 340nm, lambdaem 375nm (MeOH). The hydrazide group reacts with carbonyl groups (like aldehydes or ketones) to form hydrazones. This makes PBH useful for labeling oxidized sugars, glycoproteins, or carbonylated biomolecules. It can be used to modify surfaces (e.g. glass or nanoparticles) for biosensing applications. Also used in the derivatization of proteins, carbohydrates, or lipids that have been oxidized to expose reactive carbonyls. PBH is utilized in developing advanced optical materials, where its fluorescence properties can enhance the detection sensitivity of various biological and chemical systems.
EClass:
32160000
Form:
solid
GHS Symbol:
GHS07
Handling Advice:
Protect from light and moisture.
Hazards:
H302+H312+H332-H315-H319-H335
InChi:
InChI=1S/C20H18N2O/c21-22-18(23)6-2-3-13-7-8-16-10-9-14-4-1-5-15-11-12-17(13)20(16)19(14)15/h1,4-5,7-12H,2-3,6,21H2,(H,22,23)
InChiKey:
SOPPDVMSOKMZOC-UHFFFAOYSA-N
MDL:
MFCD00467260
Molecular Formula:
C20H18N2O
Molecular Weight:
302.37
Package Type:
Vial
Precautions:
P261-P280-P301+P312-P302+P352+P312-P304+P340+P312-P305+P351+P338
Purity:
>97% (HPLC)
Signal word:
Warning
SMILES:
O=C(NN)CCCC1=CC=C2C=CC3=CC=CC=4C=CC1=C2C34
Solubility Chemicals:
Soluble in DMSO.
Source / Host:
Synthetic
Transportation:
Non-hazardous
UNSPSC Number:
41105331
Use & Stability:
Stable for at least 2 years after receipt when stored at RT.

Documents

References

(1) S.A. Reines & C.R. Cantor; Nucleic Acids Res. 1, 767 (1974) | (2) P. Koenig, et al.; Biopolymers 16, 2231 (1977) | (3) N. Shambaugh & E. Fujimori; Biopolymers 21, 79 (1982) | (4) D. Sugahara, et al.; Anal. Sci. 19, 167 (2003) | (5) H. Yoshida, et al.; Anal. Chim. Acta 534, 177 (2005) | (6) F.V Mansano, et al.; Anal. Chem. 82, 6775 (2010) | (7) F. Novio, et al.; Chem. Eur. J. 20, 15443 (2014) | (8) R.W. Sabnis; Handbook of Fluorescent Dyes and Probes 334 (2015)