Chemodex

N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride

Product Code:
 
CDX-T0511
Product Group:
 
Dyes, Stains, and Probes
Supplier:
 
Chemodex
Regulatory Status:
 
RUO
Shipping:
 
Ambient
Storage:
 
Short term: +20°C. Long term: +20°C
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Chemical Structure

Chemical Structure

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CDX-T0511-G0055 g£64.00
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CDX-T0511-G02525 g£220.00
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This product comes from: Switzerland.
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Further Information

Appearance:
Pale-yellow solid.
CAS:
637-01-4
Description:
N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride (TMPD) is a redox-active aromatic amine compound, widely used in biochemical and analytical applications, particularly as a chromogenic redox indicator. TMPD is commonly used in redox titrations and biochemical assays. It is colorless in its reduced form and turns blue or purple (called Wurster's Blue) upon oxidation, indicating electron transfer activity. This makes it valuable for detecting the presence or activity of oxidases or cytochromes. TMPD serves as an artificial electron donor, particularly to cytochrome c oxidase (complex IV) in the mitochondrial electron transport chain. It's often used in combination with ascorbate to assess respiratory chain function. TMPD is used in colorimetric assays for peroxidase activity or other oxidoreductases, where a color change signals enzyme action.
EClass:
32160000
Form:
solid
GHS Symbol:
GHS07
Handling Advice:
Protect from light and moisture.
Hazards:
H302+H312+H332-H315-H319
InChi:
InChI=1S/C10H16N2.2ClH/c1-11(2)9-5-7-10(8-6-9)12(3)4;;/h5-8H,1-4H3;2*1H
InChiKey:
FBHKTSXMTASXFJ-UHFFFAOYSA-N
MDL:
MFCD00012482
Molecular Formula:
C10H18Cl2N2
Molecular Weight:
237.17
Package Type:
Vial
Precautions:
P261-P264-P270-P271-P280-P301+P312+P330-P302+P352+P312+P362+P364-P304+P340+P312-P305+P351+P338+P337+P313-P501
Purity:
>95% (NMR)
Signal word:
Warning
SMILES:
N(C)(C)C1=CC=C(N(C)C)C=C1.Cl
Solubility Chemicals:
Soluble in water (50mg/ml).
Source / Host:
Synthetic
Transportation:
Non-hazardous
UNSPSC Number:
41105331
Use & Stability:
Stable for at least 2 years after receipt when stored at RT.

Documents

References

(1) M.G. Mustafa & T.E. King; Arch. Biochem. Biophys. 122, 501 (1967) | (2) H.K. Kimelberg & P. Nicholls; Arch. Biochem. Biophys. 133, 327 (1969) | (3) S. Papa, et al.; FEBS Lett. 157, 15 (1983) | (4) R. Munday; Chem. Biol. Interact. 65, 133 (1988) | (5) R.M. Lorence, et al.; J. Biol. Chem. 263, 5271 (1988) | (6) E.W. de Vrind-de Jong, et al.; Appl. Environ. Microbiol. 56, 3458 (1990) | (7) C. Storle & P. Eyer; Chem. Biol. Interact. 78, 321 (1991) | (8) N. Petrovic & M. Murray; Methods Mol. Biol. 594, 129 (2010)