Chemodex

AGD

Product Code:
 
CDX-D0169
Product Group:
 
Dyes, Stains, and Probes
Supplier:
 
Chemodex
Regulatory Status:
 
RUO
Shipping:
 
Ambient
Storage:
 
Short term: +4°C. Long term: -20°C
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Chemical Structure
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Chemical Structure

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CodeSizePrice
CDX-D0169-M100100 mg£219.00
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CDX-D0169-M250250 mg£438.00
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This product comes from: Switzerland.
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Further Information

Alternate Names/Synonyms:
7-(Diethylamino)-N-(1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl)-2-oxo-2H-chromene-3-carboxamide
Appearance:
Light yellow powder.
CAS:
1456890-74-6
EClass:
32160000
Form (Short):
liquid
Handling Advice:
Keep cool and dry.Protect from light and moisture.
InChi:
InChI=1S/C18H24N2O6/c1-3-20(4-2)13-6-5-12-7-14(17(25)26-15(12)8-13)16(24)19-18(9-21,10-22)11-23/h5-8,21-23H,3-4,9-11H2,1-2H3,(H,19,24)
InChiKey:
YGMFXQGOHXJXGN-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 1456890-74-6. Formula: C18H24N2O6. MW: 364.39. Synthetic. Coumarin-based 'turn-off' fluorescent probe. Highly selective for ferrous ions (Fe(2+)) and can reversibly detect them in aqueous medium. The probe localizes to the cell membrane in living cells, where it can detect changes in Fe(2+) concentration. Molecular dynamics (MD) simulations indicate that AGD interacts with the lipid bilayer at the level of the glycerol moieties. Spectral data: Excitation=430nm; Emission=480nm (HEPES, pH 7.4 at RT).
MDL:
MFCD31656735
Molecular Formula:
C18H24N2O6
Molecular Weight:
364.39
Package Type:
Vial
Product Description:
Coumarin-based 'turn-off' fluorescent probe. Highly selective for ferrous ions (Fe(2+)) and can reversibly detect them in aqueous medium. The probe localizes to the cell membrane in living cells, where it can detect changes in Fe(2+) concentration. Molecular dynamics (MD) simulations indicate that AGD interacts with the lipid bilayer at the level of the glycerol moieties. Spectral data: Excitation=430nm; Emission=480nm (HEPES, pH 7.4 at RT).
Purity:
>95% (NMR)
SMILES:
O=C(C(C1=O)=CC2=C(O1)C=C(N(CC)CC)C=C2)NC(CO)(CO)CO
Solubility Chemicals:
Soluble in DMSO or water.
Source / Host:
Synthetic.
Transportation:
Non-hazardous
UNSPSC Category:
Fluorescent Reagents
UNSPSC Number:
41105331
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.

References

(1) O. Garcia-Beltran, et al.; Eur. J. Med. Chem. 67, 60 (2013) | (2) M.E. Aliaga, et al.; New J. Chem. 39, 3084 (2015)