Sciencell

Human Cardiac Fibroblasts - Juvenile ventricular

Product Code:
SC-6310
Product Group:
Primary Cells
Supplier:
Sciencell
Cell System:
Cardiovascular Cell System
Cell Type:
Fibroblasts
Species:
Human
Host Type:
Human
Regulatory Status:
RUO
1 / 1
❮❯

No additional charges, what you see is what you pay! *

Show prices   How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges to UK mainland customers, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • References
  • Related Products
  • Show All

Further Information

Components:
Cells only
Extra Description:
Isolated from human ventricle. HCF-av are cryopreserved at passage one and delivered frozen. Each vial contains >5 x 10^5 cells in 1 ml volume.
Long Description:
Cardiac fibroblasts (CF) provide structural support for cardiac myocytes and are responsible for extracellular matrix synthesis in the heart during growth and pathophysiological conditions. CF are an important cellular component of myocardial responses to injury and the source of paracrine growth factors. CF proliferation and synthesis of matrix is essential for scar formation at sites of myocardial infarction and cardiac fibrosis. CF have also been found to respond to mechanical loading to regulate the metabolic activity of ventricular cells, making them a good model to study the cardiac matrix remodeling using physiological (exercise) and pathological (hypertension) stressors. HCF-av from ScienCell Research Laboratories are isolated from human ventricle. HCF-av are cryopreserved at passage one and delivered frozen. Each vial contains >5 x 10^5 cells in 1 ml volume. HCF-av are characterized by immunofluorescence with antibody specific to fibronectin. HCF-av are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi. HCF-av are guaranteed to further expand for 15 population doublings under the conditions provided by ScienCell Research Laboratories. Recommended Medium - It is recommended to use Fibroblast Medium-2 (FM-2, Cat. #2331) for culturing HCF-av in vitro.

References

  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1959490/
  • https://pubmed.ncbi.nlm.nih.gov/20039269/
  • https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0007307
  • https://www.researchgate.net/publication/49799543_Proteomic_Analysis_of_Coronary_Sinus_Serum_Reveals_Leucine-Rich_alpha_2-Glycoprotein_as_a_Novel_Biomarker_of_Ventricular_Dysfunction_and_Heart_Failure
  • http://synapse.koreamed.org/Synapse/Data/PDFData/0067KJPP/kjpp-20-315.pdf
  • http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594676/pdf/jcmm0019-2341.pdf
  • https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0128655