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User guide for In Vivo Imaging with Collagen Hybridizing Peptides (sCy7.5-CHP In vivo Kit)
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Datasheets
3Helix
The Portfolio: F-CHP, R-CHP, B-CHP, sCy7.5-CHP
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Peptides
3Helix
Collagen Hybridizing Peptides (CHPs) selectively bind to the damaged collagen molecules that signify the onset of tissue injury, giving you the power to: Detect Damage Earlier, Get Definitive Proof, Monitor Damage in Real-Time. Collagen Hybridizing Peptides (CHPs) selectively target sites of active collagen remodeling, metabolic activity that is a hallmark of fibrosis, inflammation, cell invasion, and more, giving you the power to: Visualize Active Remodeling, Quantify Disease Activity, Monitor Therapeutic Response.
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Peptides
3Helix
T he dense stromal reaction in PDAC, rich in collagen, profoundly impacts tumor progression and drug delivery. Aberrant collagen remodeling is a hallmark of this aggressive cancer. Collagen Hybridizing Peptides (CHPs), with their unique ability to target denatured collagen, offer a powerful tool to visualize and quantify these critical structural changes within the PDAC microenvironment. This technology can enhance our understanding of stromal biology and potentially identify novel therapeutic strategies.
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Peptides
3Helix
The ability of CHPs to specifically target and visualize active fibrosis offers several important implications for nAMD research. Firstly, they serve as a novel tool for understanding the dynamics of fibrosis in the disease process, potentially identifying key stages for intervention. Secondly, CHPs can accelerate the development of new anti-fibrotic treatments by providing a direct and quantifiable measure of drugefficacy in preclinical studies. Finally, while currently primarily used in animal models, the potential exists to translate CHP technology into diagnostic tools for human patients, allowing for earlier detection and monitoring of subretinal fibrosis, which could ultimately lead to improved treatment strategies and visual outcomes.
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Peptides
3Helix
Collagen Hybridizing Peptides (CHPs), with their specific affinity for denatured collagen, are a unique tool which can address limitations in Myocardial Infarction research by enabling enhanced visualization and quantification of structural collagen changes associated with Myocardial Infarction.
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Peptides
3Helix
Idiopathic Pulmonary Fibrosis (IPF) is a progressive lung disease characterized by extensive damage to the collagen within lung tissue. This damage triggers excessive collagen deposition and aberrant extracellular matrix (ECM) remodeling, ultimately leading to lung stiffening and a decline in lung function. While the overabundance of collagen is a hallmark of IPF, the dynamic processes of collagens ongoing damage and remodeling have been less understood. Collagen Hybridizing Peptides (CHPs) allow researchers to probe and visualize areas where collagen is being actively remodeled. The application of CHPs is expanding our understanding of how collagen damage contributes to IPF pathology and opening new avenues for diagnosis and therapy.
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Peptides
3Helix
Procells R&D team has independently developed a range of serum-free media (SFM) for the cultivation and protein expression of HEK293, CHO, Hybridoma and VERO cells.
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Cell Culture
Elabscience
Fresh and Frozen Human Skin Samples. Discs and Sheets. Whole-, Full Thickness-, and Dermatomed-Skin. Skin cells, S9 fractions, Microsomes, Stratum Corneum.
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Biological Samples
Biopredic
Whole blood, plasma, true serum, blood cells. Human and animal blood products. Single and pool donor samples. Samples collected on large panel of anticoagulants.
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Biological Samples
Biopredic
Biopredic are a biotechnology company specializing in the design and manufacture of human and animal assay systems. Their solutions for Drug, Cosmetic, and Chemical development and testing are focused on liver, skin and blood.
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Supplier Introduction
Biopredic
abms MycOut™ (M) is simple yet effective against mycoplasma contamination, resulting in better clearance of mycoplasma compared to the leading competitors product and Penicillin/Streptomycin.
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Cell Culture
Applied Biological Materials (abm)
Microbial contamination is one of the most common challenges in cell culture laboratories, often leading to unreliable data, unsafe biologics, and wasted resources. With abms expertise and comprehensive line of microbial control products, you can ensure a reliable and high-quality cell culture experience, even under the most challenging conditions.
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Cell Culture
Applied Biological Materials (abm)
SpheroWell™ ULA Consumables deliver dependable low-attachment performance for researchers who need consistency, scalability, and ready-to-use convenience.
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Cell Culture
Applied Biological Materials (abm)
ELK Biotechnology Microsample ELISA Kits feature an extensive product line, successfully validated for over 800 hot-selling targets across human, mouse and rat species, fully empowering your cross-disciplinary research.
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ELISA
ELK Biotechnology
ELK Biotechnology is a high-tech biological company focusing on the development and production of immunological products and molecular biology products.
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Catalogue
ELK Biotechnology
Cytokines are small proteins or peptides secreted by immune and non-immune cells. They act as signaling molecules between cells and play a central role in immune regulation, inflammatory responses, hematopoiesis, tissue repair, and development. Research on cytokines provides a scientific foundation for the prevention, diagnosis, and treatment of diseases in clinical practice.
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Cytokines
ELK Biotechnology
Founded in 2013 in Wuhan Precision Medical Industry Base, ELK Biotechnology is a high-tech biological enterprise specializing in life science and immunity research. The company has 6000㎡ Iaboratory, with independent cell culture room and SPF animal room, specializing in the introduction and development of morphological pathology, cell biology, molecular biology, protein immunology, model animal related products. Its products include 8500+ ELISA kits,70+ molecular biology products and 15,000+ proteins and antibodies for scientific research. Through unremitting efforts, our products have been sold to more than 80 countries.
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Molecular Biology
ELK Biotechnology
Easy Step - Microsample - High Sensitivity - Monkey Species
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ELISA
ELK Biotechnology
Elabscience stands at the forefront of biotechnology innovation, expertly combining independent design, R&D, manufacturing and sales to deliver premier reagents and services for cell detection research.
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Cell Biology
Elabscience
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Cell Biology
Elabscience
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Cell Biology
Elabscience
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Cell Biology
Elabscience
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Cell Biology
Elabscience
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Cell Biology
Elabscience