TargetMol

Lipopolysaccharides, from S. marcescens

Product Code:
 
TAR-TSW-00816
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
 

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CodeSizePrice
TAR-TSW-00816-10mg10 mgEnquire
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TAR-TSW-00816-5mg5 mgEnquire
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TAR-TSW-00816-50mg50 mgEnquire
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This product comes from: Austria.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Lipopolysaccharides, from S. marcescens (Serratia marcescens), are endotoxins derived from the bacterium Serratia marcescens, functioning as TLR-4 activators and classified as S type LPS. These compounds activate the immune system through pathogen-associated molecular patterns (PAMPs) and stimulate the secretion of chemokines. They feature a typical tripartite structure consisting of the O-antigen, core oligosaccharide, and Lipid A. Lipopolysaccharides from S. marcescens promote NF-κB activation in mouse cells via Toll-like receptor (TLR4)/MD-2 pathways. Additionally, these lipopolysaccharides can induce apoptosis in host immune cells, thereby suppressing the host's innate immunity.
Pathway:
Immunology/Inflammation
Target:
TLR

Documents