Elabscience

Elab Fluor®647 Anti-Human/Monkey/Mouse Integrin B7 Antibody[FIB504]

Product Code:
 
AN00571M
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rat
Antibody Isotype:
 
Rat IgG2a, κ
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
FIB504
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rhesus Macaque
Application:
 
Flow Cytometry
Shipping:
 
Ice bag
Storage:
 
This product can be stored at 2-8°C for 24 months. Please protected from prolonged exposure to light and do not freeze.
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Staining of normal human peripheral blood cells with Elab Fluor<sup>®</sup> 647 Anti-Human/Monkey/Mouse Integrin β7 Antibody[FIB504] (filled gray histogram) or Elab Fluor<sup>®</sup> 647 Rat IgG2a, κ Isotype Control (empty black histogram). Cells in the lymphocytes gate were used for analysis.

Staining of normal human peripheral blood cells with Elab Fluor<sup>®</sup> 647 Anti-Human/Monkey/Mouse Integrin β7 Antibody[FIB504] (filled gray histogram) or Elab Fluor<sup>®</sup> 647 Rat IgG2a, κ Isotype Control (empty black histogram). Cells in the lymphocytes gate were used for analysis.

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CodeSizePrice
AN00571M-20Tests20Tests£134.00
Quantity:
AN00571M-100Tests100Tests£250.00
Quantity:
AN00571M-100Testsx2100Testsx2£401.00
Quantity:
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Background:
Integrin β7 is a 130 kD glycoprotein also known as integin βp. It is a member of the Ig superfamily. In association with integrin α4 or αE chain, β7 forms α4/β7 or αE/β7 heterodimer. α4/β7 (CD49d/β7, LPAM-1) is expressed on the majority of peripheral lymphocytes, on small subsets of thymocytes, and bone marrow progenitors. LPAM-1 binds to several ligands, VCAM-1, MAdCAM-1 and fibronectin, and is involved in lymphocyte adhesion and some hematopoietic progenitor cells migration. αE/β7 (CD103/β7, αIEL/β7) is expressed on intestinal intraepithelial lymphocytes (IEL), dendritic epidermal T cells, T regulatory cells, a subset of CD8+ T cells in lymph nodes and lamina propria. CD103/β7 complex is thought to play a role in lymphocyte retention via interaction with its ligand E-Cadherin.
Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Concentration:
5 uL/Test
Conjugation:
Elab Fluor®647
Expiry date:
24 months
GeneID:
369516421
Target Synonym:
VI 6T-101, VI A024, Integrin Beta7, IntegrinBeta7, Integrin B7, IntegrinB7
UNIProt ID:
P26010, P26011
Usage:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 uL of antibody per test (million cells in 100 uL staining volume or per 100 uL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

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