Elabscience

Elab Fluor®Violet 450 Anti-Mouse CD8 Antibody[YTS-169]

Product Code:
 
AN00576Q
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rat
Antibody Isotype:
 
Rat IgG2b, κ
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
YTS-169
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Application:
 
Flow Cytometry
Shipping:
 
Ice bag
Storage:
 
This product can be stored at 2-8°C for 24 months. Please protected from prolonged exposure to light and do not freeze.
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Staining of C57BL/6 murine splenocytes cells with APC Anti-Mouse CD3 Antibody[17A2] and Elab Fluor<sup>®</sup> Violet 450 Anti-Mouse CD8 Antibody[YTS-169](left) or Elab Fluor<sup>®</sup> Violet 450 Rat IgG2b, κ Isotype Control (right). Total viable cells were used for analysis.

Staining of C57BL/6 murine splenocytes cells with APC Anti-Mouse CD3 Antibody[17A2] and Elab Fluor<sup>®</sup> Violet 450 Anti-Mouse CD8 Antibody[YTS-169](left) or Elab Fluor<sup>®</sup> Violet 450 Rat IgG2b, κ Isotype Control (right). Total viable cells were used for analysis.

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CodeSizePrice
AN00576Q-50Tests50Tests£81.00
Quantity:
AN00576Q-100Tests100Tests£96.00
Quantity:
AN00576Q-100Testsx2100Testsx2£114.00
Quantity:
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Background:
CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked α and β chains that form the α(CD8a)/β(CD8b) heterodimer and α/α homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 α/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR α/β T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 α/α homodimer is expressed on a subset of γ/δ TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck.
Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Concentration:
5 uL/Test
Conjugation:
Elab Fluor®Violet 450
Expiry date:
24 months
GeneID:
12525
Target Synonym:
T8, Lyt2, Ly-2
UNIProt ID:
P01731
Usage:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 uL of antibody per test (million cells in 100 uL staining volume or per 100 uL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

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