Further Information
CD131, also known as the IL-3R common β subunit (βC), is a 95-120 kD type I transmembrane glycoprotein and belongs to the Ig superfamily. The common β subunit associates with the specific α subunits of IL-3 receptor, IL-5 receptor and GM-CSF receptor to form high affinity receptors for these cytokines. These cytokine receptors are expressed by neutrophils, eosinophils, monocytes, endothelial cells, fibroblasts and hematopoietic progenitor cells and play a crucial role in growth/activation of eosinophils and in the inflammatory response.
Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
≥ 1 mg/mL
Unconjugated
FCM 2 ug/mL(0.5x106-1x106 cells)
12 months
Recombinant Human CD131 protein
>98%, Protein A/G purified
/granulocyte-macrophage colony-stimulating factor receptor, beta, beta (high affinity), Beta-C, CDw131, Colony stimulating factor 2 receptor beta, Colony stimulating factor 2 receptor beta low affinity (granulocyte macrophage), Common beta chain, Cytokine receptor common beta chain, Cytokine receptor common beta chain precursor (CDw131 antigen), Cytokine receptor common subunit beta, GM CSF/IL 3/IL 5 receptor common beta chain, GM-CSF/IL-3/IL-5 receptor common beta subunit, Interleukin 3 receptor, Interleukin 3 receptor/granulocyte macrophage colony stimulating factor 3 receptor beta (high affinity), Interleukin 5 receptor, SMDP5, stimulating factor 3 receptor, CD131, IL3RB, IL5RB, CSF2RB, common &, beta- chain-n, CDw131, IL-3R&, beta
P32927