Elabscience

PE/Cyanine 5.5 Anti-Human CD195/CCR5 Antibody[HEK/1/85a]

Product Code:
 
E-AB-F1392I
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Mouse
Antibody Isotype:
 
Rat IgG2a, κ
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
HEK/1/85a
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Flow Cytometry
Shipping:
 
Ice bag
Storage:
 
This product can be stored at 2-8°C for 24 months. Please protected from prolonged exposure to light and do not freeze.
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Staining of normal human peripheral blood cells with FITC Anti-Human CD3 Antibody[OKT-3] and PE/Cyanine 5.5 Anti-Human CD195 Antibody[HEK/1/85a/7a] (left) or PE/Cyanine 5.5 Rat IgG2b, κ Isotype Control (right). Cells in the lymphocytes gate were used for analysis.
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Staining of normal human peripheral blood cells with FITC Anti-Human CD3 Antibody[OKT-3] and PE/Cyanine 5.5 Anti-Human CD195 Antibody[HEK/1/85a/7a] (left) or PE/Cyanine 5.5 Rat IgG2b, κ Isotype Control (right). Cells in the lymphocytes gate were used for analysis.

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CodeSizePrice
E-AB-F1392I-20Tests20Tests£136.00
Quantity:
E-AB-F1392I-100Tests100Tests£238.00
Quantity:
E-AB-F1392I-100Testsx2100Testsx2£325.00
Quantity:
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Further Information

Background:
CD195, also known as CCR5, is a 45 kD G protein-coupled seven transmembrane CC-chemokine receptor. It binds to MIP-1α, MIP-1β, and RANTES and is expressed on a subset of T cells and monocytes. CD195 mediates an intracellular signal thought to induce cell differentiation and proliferation. CCR5 has also been shown to act as a co-receptor for R5 HIV-1 cell entry, modification of CCR5 by sulfation contributes to the efficiency of HIV-1 entry. Recent studies have shown CCR5 to play a role in a variety of other human diseases, ranging from infectious and inflammatory diseases to cancer.
Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Concentration:
5 uL/Test
Conjugation:
PE/Cyanine 5.5
Expiry date:
24 months
GeneID:
1234
Target Synonym:
CCR5, C-C chemokine receptor type 5, HIV-1 fusion co-receptor
UNIProt ID:
P51681
Usage:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 uL of antibody per test (million cells in 100 uL staining volume or per 100 uL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

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