Elabscience

APC Anti-Rat CD172a Antibody[OX-41]

Product Code:
 
AN00652E
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Mouse
Antibody Isotype:
 
Mouse IgG2a, κ
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
OX-41
Regulatory Status:
 
RUO
Target Species:
 
Rat
Application:
 
Flow Cytometry
Shipping:
 
Ice bag
Storage:
 
This product can be stored at 2-8°C for 24 months. Please protected from prolonged exposure to light and do not freeze.
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Staining of Rat bone marrow cells with APC Anti-Rat CD172a Antibody[OX-41] (left) or APC Mouse IgG2a Isotype Control (right). Cells in the Granulocytes gate were used for analysis.
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Staining of Rat bone marrow cells with APC Anti-Rat CD172a Antibody[OX-41] (left) or APC Mouse IgG2a Isotype Control (right). Cells in the Granulocytes gate were used for analysis.

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CodeSizePrice
AN00652E-50Tests50Tests£85.00
Quantity:
AN00652E-100Tests100Tests£105.00
Quantity:
AN00652E-100Testsx2100Testsx2£139.00
Quantity:
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Background:
Rat CD172a, also known as a signal-regulatory protein fake (SIRPfake), is a 75-110 kD transmembrane glycoprotein involved in the receptor tyrosine kinase coupled signaling pathway. It belongs to the Ig superfamily primarily expressed on monocytes/macrophages, granulocytes, dendritic cells and neurons. CD172a serves as a substrate of activated receptor ttyrosine kinases (RTKs). The interaction of the CD172a intracellular domain with SHP-1 and SHP-2 displays negative signaling in the regulation of leukocyte adhesion and transmigration, T cell activation, macrophage fusion and phagocytosis. CD47 (IAP) is an extracellular ligand for CD172a.
Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Concentration:
5 uL/Test
Conjugation:
APC
Expiry date:
24 months
GeneID:
19261
Target Synonym:
SIRPa, PTPNS1, BIT, MFR, p84, CD172 antigen-like family member A
UNIProt ID:
P97710
Usage:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 uL of antibody per test (million cells in 100 uL staining volume or per 100 uL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

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