Elabscience

PE Anti-Human CD16 Antibody[B73.1]

Product Code:
 
AN00950D
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Mouse
Antibody Isotype:
 
Mouse IgG1, κ
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
B73.1
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Flow Cytometry
Shipping:
 
Ice bag
Storage:
 
This product can be stored at 2-8°C for 24 months. Please protected from prolonged exposure to light and do not freeze.
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Staining of normal human peripheral blood cells with PE Anti-human CD16 Antibody[B73.1] (filled gray histogram) or PE Mouse IgG1, κ Isotype Control (empty black histogram). Cells in the lymphocytes gate were used for analysis.
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Staining of normal human peripheral blood cells with PE Anti-human CD16 Antibody[B73.1] (filled gray histogram) or PE Mouse IgG1, κ Isotype Control (empty black histogram). Cells in the lymphocytes gate were used for analysis.

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CodeSizePrice
AN00950D-20Tests20Tests£120.00
Quantity:
AN00950D-100Tests100Tests£223.00
Quantity:
AN00950D-100Testsx2100Testsx2£353.00
Quantity:
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Background:
CD16 is known as low affinity IgG receptor III (FcγRIII). It is expressed as two distinct forms (CD16a and CD16b). CD16a (FcγRIIIA) is a 50-65 kD polypeptide-anchored transmembrane protein. It is expressed on the surface of NK cells, activated monocytes, macrophages, a subset of T cells and placental trophoblasts in humans. CD16b (FcγRIIIB) is a 48 kD glycosylphosphatidylinositol (GPI)-anchored protein. Its extracellular domain is over 95% homologous to that of CD16a, and it is expressed specifically on neutrophils. CD16 binds aggregated IgG or IgG-antigen complex which functions in NK cell activation, phagocytosis, and antibody-dependent cell-mediated cytotoxicity (ADCC).
Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Concentration:
5 uL/Test
Conjugation:
PE
Expiry date:
24 months
GeneID:
22142215
Target Synonym:
FcγRIII, IGFR3, FCG3, FCGR3, FCGRIII, Fc gamma receptor, Fc gamma receptor 3, CD16a
UNIProt ID:
P08637
Usage:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 uL of antibody per test (million cells in 100 uL staining volume or per 100 uL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

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