Elabscience

PE/Cyanine 7 Anti-Human CD244 Antibody[C1.7]

Product Code:
 
E-AB-F1374H
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Mouse
Antibody Isotype:
 
Mouse IgG1, κ
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
C1.7
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Flow Cytometry
Shipping:
 
Ice bag
Storage:
 
This product can be stored at 2-8°C for 24 months. Please protected from prolonged exposure to light and do not freeze.
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Staining of normal human peripheral blood cells with FITC Anti-Human CD8a Antibody and PE/Cyanine7 Anti-Human CD244 Antibody[C1.7] (left) or PE/Cyanine7 Mouse IgG1, κ Isotype Control (right). Cells in the lymphocytes gate were used for analysis.
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Staining of normal human peripheral blood cells with FITC Anti-Human CD8a Antibody and PE/Cyanine7 Anti-Human CD244 Antibody[C1.7] (left) or PE/Cyanine7 Mouse IgG1, κ Isotype Control (right). Cells in the lymphocytes gate were used for analysis.

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CodeSizePrice
E-AB-F1374H-20Tests20Tests£136.00
Quantity:
E-AB-F1374H-100Tests100Tests£274.00
Quantity:
E-AB-F1374H-100Testsx2100Testsx2£378.00
Quantity:
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This product comes from: China.
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Further Information

Background:
CD244, known as 2B4, is a 38 kD type I transmembrane protein. It is a member of the CD2 subset of the immunoglobulin superfamily (IgSF) molecules. CD244 is expressed on NK cells, a subset of T cells (including most CD8+ T cells and γ/δ T cells), monocytes, basophils, and eosinophils. CD48 is the ligand of CD244. It has been reported that ligation of human CD244 results in enhanced NK cell cytotoxicity and cytokine production. Recent studies have shown that human CD244, like murine CD244, has both activating and inhibitory functions, which are dependent on the density of surface 2B4 expression, degree of ligation, and the level of the adaptor molecule SAP expression.
Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Concentration:
5 uL/Test
Conjugation:
PE/Cyanine 7
Expiry date:
24 months
GeneID:
51744
Target Synonym:
2B4, SLAMF4
UNIProt ID:
Q9BZW8
Usage:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 uL of antibody per test (million cells in 100 uL staining volume or per 100 uL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

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