Leinco Technologies offers both GOLD™ and PLATINUM™ In vivo functional grade antibodies to important checkpoint markers for use in checkpoint research.
Immune Checkpoint Mechanism of Action
![Immune Checkpoint Mechanism of Action Immune Checkpoint Mechanism of Action](https://www.caltagmedsystems.co.uk/information/wp-content/uploads/leinco-blog-post-logo-600x300.png)
Leinco Technologies offers both GOLD™ and PLATINUM™ In vivo functional grade antibodies to important checkpoint markers for use in checkpoint research.
Negative controls aid precision of immune response monitoring. For HLA-A*02:01 alleles, MBLI offers a “Negative Tetramer” in BV421, PE or APC.
ProSci offers reagents that can be used to study the actions of multiple immune checkpoint proteins such as CTLA-4, PD-1, & its ligands PD-L1 & PD-L2.
Research continues in understanding mechanisms of SARS-CoV-2 immune evasion. ProSci offers antibodies & recombinant proteins for SARS-CoV-2 research.
The human leukocyte antigen system, aka human major histocompatibility complex, was named after its discovery with alloantibodies against leukocytes.
This white paper details findings in molecular mechanisms that govern necroptosis related to RIPK & details #2283 use to analyse expression of RIPK3.
ProSci has 25+ years expertise in developing antibodies. This white paper details use of RIPK antibodies & findings on RIPKs in signalling pathways.
ProSci details the importance of PD-1 antibodies are important in resolving complex interactions between the immune system & pathological conditions.
MBL International offers CD1d tetramers prepared by tetramerisation of complexes of CD1d and β2m by PE- or APC- labelled streptavidin.
Recently 5 new B7 family ligands, B7-H3, B7-H4, B7-H5, B7-H6 & B7-H7, were identified, all of them possibly of high interest in immunotherapy research.