Sciencell

GeneQuery™ Human Autism Spectrum Disorder qPCR Array Kit

Product Code:
 
SC-GK077
Product Group:
 
PCR Kits
Supplier:
 
Sciencell
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
PCR
1 / 1
❮❯

No additional charges, what you see is what you pay! *

Show prices   How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges to UK mainland customers, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • Related Products
  • Show All

Further Information

Description:
ScienCell's GeneQuery™ Human Autism Spectrum Disorder qPCR Array Kit (GQH-ASD) profiles 88 key genes associated with autism spectrum disorder. Autism spectrum disorder is a developmental disability that can result in social, communication, behavioral, and learning challenges. The disease is early-appearing, with symptoms often presenting early in childhood, and evidence suggests there is a strong hereditary component. Below are brief examples of how included genes may be grouped according to their function:
  • Neurodevelopment - : ADNP, ANKRD11, ARID1B, ASH1L, ASXL3, AUTS2, BCL11A, CACNA1H, CHD2, DISC1, DSCAM, FOXP1, GRIN2B, KATNAL2, KDM6B, KMT2C, MET, NCKAP1, NRXN3, PHF2, POGZ, RBFOX1, RELN, RIMS, SEMA5A, SHANK2, TCF4, ZBTB20
  • Impaired - communication/behavioral ability - : CNTNAP2, FOXP2, GRIK2, KMT2A, KMT5B, MACROD2, MED13L, PAX5, PTEN, SHANK3, SPAST
  • Social deficits/behavioral abnormalities: - AVPR1A, BCKDK, CNTNAP4, DIP2A, GRIP1, HMGN1
  • Calcium signaling/calcium channels: - ATP2B2, CACNB2, CDC42BPB, PRKCB
  • Altered expression linked to ASD: - ASTN2, CACNA2D3, CHD8, CHRNA7, CTCF, CTTNBP2, FOXP1, GABRB3, GPHN, GRIP1, KDM5B, MBD5, MYT1L, NLGN3, NR3C2, NRXN1, PTCHD1, SETBP1, SETD5, SYNGAP1, TBR1, TRIO, TRIP12, ZMYND11, WAC, WDFY3
  • Novel variants found in ASD - : DEAF1, MAGEL2, TNRC6B, TRPC6
  • Other risk factors for autism - : CACNA1D, CHD8, CTNND2, CUL3, MACROD2, MECP2, OXTR, SCN2A, SLC9A9
  • Linked to non-syndromic autism - : ANK2, KMT2E, NLGN4X, TRPC6, SHANK3
GeneQuery™ qPCR array kits are qPCR ready in a 96-well plate format, with each well containing one primer set that can specifically recognize and efficiently amplify a target gene's cDNA. The carefully designed primers ensure that: (i) the optimal annealing temperature in qPCR analysis is 65°C (with 2 mM Mg^2+ , and no DMSO); (ii) the primer set recognizes all known transcript variants of target gene, unless otherwise indicated; and (iii) only one gene is amplified. Each primer set has been validated by qPCR with melt curve analysis, and gel electrophoresis.
Extra Description:
ScienCell's GeneQuery™ Human Autism Spectrum Disorder qPCR Array Kit (GQH-ASD) profiles 88 key genes associated with autism spectrum disorder.