TargetMol

(+)-Fluprostenol

Product Code:
 
TAR-T21224
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T21224-1mL1 mL * 10 mM (in DMSO)Enquire
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This product comes from: Austria.
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  • Further Information
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Further Information

Bioactivity:
(+)-Fluprostenol, an analogue of prostaglandin F2 alpha, is a prostaglandin F2α receptor PTGFR agonist and decreases the expression of Oviductal glycoprotein 1 (OVGP1).
CAS:
54276-17-4
Formula:
C23H29F3O6
Molecular Weight:
458.474
Pathway:
GPCR/G Protein; Immunology/Inflammation
Purity:
0.9956
SMILES:
O[C@@H](COc1cccc(c1)C(F)(F)F)C=C[C@H]1[C@H](O)C[C@H](O)[C@@H]1CC=C/CCCC(O)=O
Target:
Prostaglandin Receptor

Documents

References

1. Baryla M, Kaczynski P, Goryszewska E, Riley SC, Waclawik A. Prostaglandin F(2?) stimulates adhesion, migration, invasion and proliferation of the human trophoblast cell line HTR-8/SVneo. Placenta. 2019 Feb;77:19-29. doi: 10.1016/j.placenta.2019.01.020. Epub 2019 Jan 24. PubMed PMID: 30827352. 2. Gao L, Gao R, Mao W, Liu B, Zhang S, Tahala D, Fu C, Shen Y, Wu J, Deng Y, Li Q, Cao J. PTGFR activation promotes the expression of PTGS-2 and growth factors via activation of the PKC signaling pathway in bovine endometrial epithelial cells. Anim Reprod Sci. 2018 Dec;199:30-39. doi:10.1016/j.anireprosci.2018.10.003. Epub 2018 Oct 14. PubMed PMID: 30340853. 3. Zhang S, Liu B, Gao L, Mao W, Fu C, Duritahala D, Zhang N, Zhang Y, Shen Y, Cao J. Prostaglandin F(2?)-PTGFR signalling activation, growth factor expression and cell proliferation in bovine endometrial explants. Reprod Fertil Dev. 2017 Oct;29(11):2195-2205. doi: 10.1071/RD16144. PubMed PMID: 28298246. 4. Ahmad SF, Akoum A, Horne AW. Selective modulation of the prostaglandin F2? pathway markedly impacts on endometriosis progression in a xenograft mouse model. Mol Hum Reprod. 2015 Dec;21(12):905-16. doi: 10.1093/molehr/gav056. Epub 2015 Oct 15. PubMed PMID: 26472819.