TargetMol

PF-00217830

Product Code:
 
TAR-T24613
Product Group:
 
Other Biochemicals
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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This product comes from: Austria.
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  • Further Information
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Further Information

Bioactivity:
PF-00217830 is a Serotonin 1A receptor agonist, Dopamine D2 receptor agonist, and Serotonin 2A receptor antagonist.
CAS:
846032-02-8
Formula:
C26H30N4O2
Molecular Weight:
430.552
Pathway:
Neuroscience|GPCR/G Protein
Purity:
0.98
SMILES:
O=C1CCc2ccc(OCCCCN3CCN(CC3)c3cccc4ccccc34)nc2N1
Target:
Dopamine Receptor|Serotonin Transporter

Documents

References

1. Zhao SX, Wang WW, Walker GS, Zhang L, Obach RS. Metabolism of a dopamine receptor partial agonist in rats, including an unusual N-dearylation reaction. Drug Metab Pharmacokinet. 2011 Jun;26(3):266-79. doi: 10.2133/dmpk.DMPK-10-RG-109. Epub 2011 Mar 4. PubMed PMID: 21383524. 2. Johnson DS, Choi C, Fay LK, Favor DA, Repine JT, White AD, Akunne HC, Fitzgerald L, Nicholls K, Snyder BJ, Whetzel SZ, Zhang L, Serpa KA. Discovery of PF-00217830: aryl piperazine napthyridinones as D2 partial agonists for schizophrenia and bipolar disorder. Bioorg Med Chem Lett. 2011 May 1;21(9):2621-5. doi: 10.1016/j.bmcl.2011.01.059. Epub 2011 Jan 22. PubMed PMID: 21353774.