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Further Information
Bioactivity:
N3-C4-NHS ester is a non cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
1. Pyrrolobenzodiazepine Dimer Antibody-Drug Conjugates: Synthesis and Evaluation of Noncleavable Drug-Linkers. J Med Chem. 2017 Dec 14;60(23):9490-9507.