Chemodex

5-FAM

Product Code:
 
CDX-C0014
Product Group:
 
Dyes, Stains, and Probes
Supplier:
 
Chemodex
Regulatory Status:
 
RUO
Shipping:
 
Ambient
Storage:
 
Short term: +4°C. Long term: +4°C
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Chemical Structure
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Chemical Structure

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CDX-C0014-M02525 mg£54.00
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CDX-C0014-M100100 mg£140.00
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CDX-C0014-G0011 g£1,039.00
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Further Information

Alternate Names/Synonyms:
5-Carboxyfluorescein
Appearance:
Yellow-orange solid.
CAS:
76823-03-5
EClass:
32160000
Form (Short):
liquid
Handling Advice:
Protect from light and moisture.
InChi:
InChI=1S/C21H12O7/c22-11-2-5-14-17(8-11)28-18-9-12(23)3-6-15(18)19(14)13-4-1-10(20(24)25)7-16(13)21(26)27/h1-9,22H,(H,24,25)(H,26,27)
InChiKey:
VPMWLNJETPKSSC-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 76823-03-5. Formula: C21H12O7. MW: 376.32. Synthetic. The amine-reactive fluorescein derivatives are probably the most common fluorescent derivatization reagents for covalently labeling proteins. Carboxyfluorescein is better retained in cells than is fluorescein, its pKa of ~6.5 is lower than the cytosolic pH of most cells (pH ~6.8-7.4). Carboxyfluorescein is commonly employed as a polar tracer.
MDL:
MFCD00036874
Molecular Formula:
C21H12O7
Molecular Weight:
376.32
Package Type:
Vial
Product Description:
The amine-reactive fluorescein derivatives are probably the most common fluorescent derivatization reagents for covalently labeling proteins. Carboxyfluorescein is better retained in cells than is fluorescein, its pKa of ~6.5 is lower than the cytosolic pH of most cells (pH ~6.8-7.4). Carboxyfluorescein is commonly employed as a polar tracer.
Purity:
>99% (HPLC)
SMILES:
OC(=O)C1=CC=C(C(=C1)C(O)=O)C1=C2C=CC(=O)C=C2OC2=CC(O)=CC=C12
Solubility Chemicals:
Soluble in water, DMSO or DMF.
Source / Host:
Synthetic.
Transportation:
Non-hazardous
UNSPSC Category:
Fluorescent Reagents
UNSPSC Number:
41105331
Use & Stability:
Stable for at least 2 years after receipt when stored at +4°C.

References

(1) R. Fischer et al. Bioconjugate Chem. 14, 653 (2003) | (2) E. Ralston et al. Biochim. Biophys. Acta, Biomembranes 649(1), 133 (1981)