immunAware’s stability assay measures dissociation of pMHC complexes at 37°C. Distinguish between peptides that support formation of stable or unstable pMHC complexes.
State-of-the art pMHC stability assessment
easYmers® peptide loadable MHC class I
With immunAware’s peptide receptive easYmers®, you can produce pMHC complexes tailored for your project, in your own lab!
Peptide-MHC monomers and tetramers
immunAware provide MHC monomers and tetramers for peptide-Class I, peptide-Class II and custom epitopes.
immunAware Custom MHC Complexes
Choose from over 100 HLA class I and class II allotypes ready to be loaded with your chosen peptide for custom production of pMHC complexes.
KACTUS: MHC Monomer & Tetramer Product Validation Data
KACTUS has demonstrated via ELISA & SPR binding assays that their MHC-peptide complexes & loaded peptide-ready MHCs have good binding affinity to TCRs.
KACTUS: MHC Monomer & Tetramer Alleles
KACTUS have a range of Class I and Class II MHC Monomer and Tetramer alleles available.
Analytical Tools
All the analytical tools you need for your research: in vivo products, tetramers, ELISAs, small molecules & proteins (RUO & GMP)!
TCR Tetramers
A TCR Tetramer is a reagent prepared by tetramerising biotinylated antigen-specific TCRs with the help of phycobiliprotein-labelled streptavidin.
HLA-E Non-classical MHC Tetramers
Non-classical Major Histocompatibility Complex (MHC) molecules are non-polymorphic proteins implicated in both innate and adaptive immune responses.1,2 While classical MHCs present antigens to CD8+/CD4+ cells for further immune processing, non-classical MHCs also mediate activation or inhibition in natural killer (NK) cells.3 MBL
CD1d
CD1d molecules are non-polymorphic MHC class I-like proteins. These are a type of non-classical MHCs. They present phospholipid and glycosphingolipid antigens to invariant Natural Killer T (iNKT) cells, a subset of CD1d-restricted T cells. This axis is involved in the