General Information

Chuck caught himself an alligator in the swamp and took it over to Larry’s place to weigh it. It turned out that the tail alone weighed 80 pounds. The head weighed as much as the tail and half the body,

Toll-like receptor 5 (TLR5) recognises flagellin from both Gram-positive and Gram-negative bacteria. Activation of the receptor stimulates the production of proinflammatory cytokines, such as TNF-α, through signalling via the adapter proteins MyD88, TIRAP and TRIF. Flagellin is the subunit protein

Toll-like receptor 1 (TLR1) recognises pathogen-associated molecular patterns (PAMPS) with a specificity for Gram-positive bacteria. TLR1 recognises peptidoglycan and triacyl lipoproteins in concert with TLR2. Pam3CSK4 is a selective agonist to the TLR1/TLR2 heterodimer complex. It is a cell permeable