ProSci Inc. offers an extensive range of antibodies and supporting tools to research CD80. Read more about their range below, or click a link to jump to a specific section:
- Risk-Free™ Mouse Monoclonal CD80 Products
- Risk-Free™ Single Domain Monoclonal CD80 Products
- Related Products
- Additional CD80 Antibody Products
- Additional CD80 Information
CD80, also known as B7-1, is a type I membrane protein that is a member of the immunoglobulin superfamily that is expressed by antigen-presenting cells. Like the related protein CD86, this protein is expressed by antigen-presenting cells and is the ligand for CD28 and CTLA-4 at the cell surface of T cells. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell and induces T-cell proliferation and cytokine production.
Risk-Free™ Mouse Monoclonal CD80 Products
ProSci’s Risk-Free™ antibodies are monoclonal antibodies made to improve in vivo studies. Unlike antibodies developed using proteins made in yeast or bacteria, Risk-Free™ antibodies are developed with antigens expressed in mammalian cell lines, giving the most native post-translational modifications to the protein. Risk-Free™ means they are guaranteed to work for their approved applications.
Risk-Free™ Mouse Monoclonal CD80 Set
ProSci’s Risk-Free™ Sets consists of several mAbs with different binding features allowing selection of the best clone.
| Product Set | Size | Contents | Description |
|---|---|---|---|
| Risk-Free CD80 Set (PSI-RF16040) | 20μg / Clone | PSI -RF16041, PSI-RF16042, PSI-RF16043, PSI-RF16044, PSI-RF16045, PSI-RF16046 | CD80 antibodies were raised against the extracellular domain of human CD-80. |
Risk-Free™ Mouse Monoclonal CD80 Antibodies
ProSci Risk-Free™ CD80 products are rigorously tested and guaranteed to work for their designated applications.
| Cat. No | ELISA | WB | ICC | IF | IHC | Flow | Conjugation |
|---|---|---|---|---|---|---|---|
| PSI-RF16041 | ++ | - | ++++ | ++++ | ++++ | ++++ | Available |
| PSI-RF16042 | ++ | - | ++++ | ++++ | ++++ | ++++ | Available |
| PSI-RF16043 | + | - | ++++ | ++++ | +++ | - | Available |
| PSI-RF16044 | + | - | ++++ | ++++ | +++ | ++++ | Available |
| PSI-RF16045 | ++++ | ++++ | ++++ | ++++ | ++++ | + | Available |
| PSI-RF16046 | ++++ | ++++ | ++++ | ++++ | ++++ | + | Available |
(blank)= Not Yet Determined|- = Negative|+ = Fair|++ = Average|+++ = Good|++++ = Excellent
Risk-Free™ Single Domain Monoclonal CD80 Products
Llama single domain antibodies (sdAbs) offer unique characteristics amenable to many applications. These sdAbs demonstrate low nanomolar binding affinity and can be used for the various applications. Note: CD80 single domain antibody should be stored in working aliquots at -20°C, stable for up to one year. As with all antibodies, care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Related Products
Antigen-
| Cat. No | Product Type | Species | Tissue/Cell |
|---|---|---|---|
| PSI-RF16040-01 | Recombinant Protein | Human | Human Cells |
Lysates-
| Cat. No | Product Type | Species | Tissue/Cell |
|---|---|---|---|
| PSI-RF10001-06 | Positive Control (Cell Lysate) | Human | Raji |
| PSI-RF10001-04 | Positive Control (Tissue Lysate) | Human | Tonsil |
| PSI-RF10001-02 | Negative Control (Cell Lysate) | Human | HEK293 |
Slides-
| Cat. No. | Product Type | Species | Tissue/Cell |
|---|---|---|---|
| PSI-RF10002-04 | Positive Control (Cells) | Human | Raji |
| PSI-RF10002-02 | Negative Control (Cells) | Human | HEK293 |
Conjugates-
| Cat. No. | HRP | Biotin | Custom |
|---|---|---|---|
| PSI-RF16041 | Enquire | Contact Us | |
| PSI-RF16042 | Enquire | Contact Us | |
| PSI-RF16043 | Enquire | Contact Us | |
| PSI-RF16044 | Enquire | Contact Us | |
| PSI-RF16045 | Enquire | Contact Us | |
| PSI-RF16046 | Enquire | Contact Us |
Additional CD80 Antibody Products
Monoclonal antibodies are highly specific and recognize only one epitope on an antigen which generates consistent performance in quantitative detection applications regardless of production batch. Polyclonal antibodies have high affinity and recognize different epitopes on a specific antigen. Note: These antibodies can be stored at -20˚C and are stable for up to one year. Antibodies should not be exposed to prolonged high temperatures.
CD80 Monoclonal Products
| Cat. No. | Name | Applications |
|---|---|---|
| PSI-51-377 | CD80 Antibody [2A2] | ELISA, IF, IHC |
| PSI-76-040 | CD80 Antibody [16-10A1] | Flow, Func, IHC, IF, IP |
| PSI-76-042 | CD80 Antibody [16-10A1] (FITC) | Flow |
| PSI-76-045 | CD80 Antibody [16-10A1] (PE) | Flow |
| PSI-76-047 | CD80 Antibody [16-10A1] (APC) | Flow |
| PSI-76-049 | CD80 Antibody [3H5] (PE) | Flow |
CD80 Polyclonal Products
| Cat. No. | Antigen Range | ELISA | WB | ICC | IF | IHC | Flow |
|---|---|---|---|---|---|---|---|
| PSI-8679 | 60 - 110 | ++++ | ++++ | ++++ | ++++ | ||
| PSI-42-780 | 201 - 250 | +++ | |||||
| PSI-61-757 | 260 - 288 | +++ | ++++ | ||||
| PSI-XP-5104 | 1 - 288 | ||||||
| PSI-XP-5104Bt | 1 - 288 |
(blank)= Not Yet Determined|- = Negative|+ = Fair|++ = Average|+++ = Good|++++ = Excellent
CD80 Recombinant Protein Products
| Cat. No. | Sequence | Fusion Tag | Species | Tissue/Cell |
|---|---|---|---|---|
| PSI-90-399 | Aa 35 - 237 | Fc Tag | Human | CHO |
| PSI-90-400 | Aa 35 - 142 | Fc Tag | Human | CHO |
| PSI-90-401 | Aa 37 - 245 | Fc Tag | Mouse | CHO |
| PSI-92-581 | Val 38 - Lys 245 | C-Fc Tag | Mouse | Human |
| PSI-96-044 | Val 35 - Asn 242 | His Tag | Human | HEK293 |
| PSI-96-045 | Val 35 - Asn 242 | C-Fc Tag | Human | HEK293 |
| PSI-96-085 | Ala 37 - Ser 160 | His Tag | Cynomolgus monkey | HEK293 |
CD80 Peptide Products
| Cat. No. | Location | Species |
|---|---|---|
| PSI-42-780P | A synthetic peptide corresponding to the internal region of CD80 | Human |
| PSI-8679P | 17 amino acid peptide near the amino terminus of human CD80 | Human |
Additional CD80 Information
- Genecards: CD80 Database
- Blog: The Purpose of CD80/CD86
- Flyer: Immune Checkpoints
- Video: What is Immune Checkpoint Therapy?
ProSci products are distributed across Europe by Caltag Medsystems. If you have any questions about the products in this blog, please contact us.