All the tools you need for genetical modifications: vectors, viral delivery systems, transfection and transduction reagents…even lipid nanoparticles!
Genetic Tools
Understanding ECM Remodelling in Full-Thickness Skin Grafts: Insights from Collagen Hybridising Peptide Staining
Using CHP staining, researchers observed active collagen turnover in grafts, indicating that the ECM was being actively remodelled.
Potent Neutralisation of Sars-CoV-2 Including Variants of Concern by Vaccines Presenting the Receptor-binding Domain Multivalently from Nanoscaffolds
RBD-SpyCatcher-mi3 vaccine construct could be a promising candidate for broad protection against SARS-CoV-2 variants, advocating for further clinical testing.
nanoCAR-T mRNA Service
Non-viral chimeric antigen receptor (CAR)-T cells are gaining attention for their cancer-killing ability with reduced side effects. Traditional CAR-T cell engineering relies on lentivirus, which causes random chromosomal integration, permanent CAR expression, and adverse effects from persistent immunologic stimulation. To
Advancing Intervertebral Disc Degeneration Assessment with Collagen Hybridising peptides: A Fast, Accurate Approach for Research and Clinical Applications
Collagen Hybridising Peptides (CHPs) selectively bind to damaged collagen, allowing precise visualisation and quantification of IVD in tissue samples.
Using Collagen Hybridising Peptides to Improve IPF Diagnosis and Imaging
This study uses collagen hybridising peptides (CHPs) to bind specifically to denatured collagen and detect fibrosis.
Collagen Hybridising Peptides Conjugated to Water-Soluble Copolymers for Targeting Intratibial Osteosarcoma
This paper explores conjugating CHPs to water-soluble N-(2-hydroxypropyl)methacrylamide (HPMA) copolymers for tumor targeting and drug delivery.
FGF-Max: Quality Assay Results
FGF-Max – a recombinant chimeric protein with features of both FGF-1 and FGF-2
What are the Differences Between Organoids and Spheroids?
In general, there are two major differences: nature of the driving force for development and length of time 3D cultures can be maintained.
Discovery Of PF-06928215 As A High-Affinity Inhibitor of cGAS Enabled by a Novel Fluorescence Polarisation Assay
ProSci’s Custom Antibody Services were used to develop a mouse monoclonal antibody against cGAMP in a recent study.